Chemical Biology

map of chem bio

Chemical Biology Faculty

Helen Blackwell

Position title: Norman C. Craig Professor of Chemistry

Email: blackwell@chem.wisc.edu

Eszter Boros

Position title: Associate Professor

Email: eboros@wisc.edu

Eszter Boros obtained her B.Sc. (2006) and her M.Sc. (2007) at the University of Zurich and her Ph.D. (2011) in Chemistry from the University of British Columbia. She was a postdoctoral fellow (2011-2015) and later…

Andrew R. Buller

Position title: Associate Professor of Chemistry

Email: arbuller@wisc.edu

Joshua J. Coon

Position title: Professor of Biomolecular Chemistry and Chemistry

Email: jcoon@chem.wisc.edu

Katrina Forest

Position title: Professor of Bacteriology and Chemistry

Email: forest@bact.wisc.edu

Ying Ge

Position title: Professor of Cell and Regenerative Biology and Chemistry

Email: ge2@wisc.edu

Samuel H. Gellman

Position title: Irving Shain Chair of Chemistry, Professor of Chemistry, Vilas Research Professor, Ralph F. Hirschmann Professor of Chemistry

Email: gellman@chem.wisc.edu

Aaron Hoskins

Position title: Professor of Biochemistry and Chemistry

Email: ahoskins@wisc.edu

Xuhui Huang

Credentials: Director, Theoretical Chemistry Institute

Position title: Hirschfelder Chair in Theoretical Chemistry, Professor of Chemistry

Email: xhuang448@wisc.edu

Our research is in the area of Theoretical Chemistry and Molecular Biophysics. The operation of biological molecules is a highly dynamic process that relies on numerous functional conformational changes. We are interested in elucidating the dynamics of these conformational changes by developing new methods based on statistical mechanics that can bridge the gap between experiments and atomistic molecular dynamics (MD) simulations.

Song Jin

Position title: Francis J. DiSalvo Professor of Physical Science

Email: jin@chem.wisc.edu

Lingjun Li

Position title: Professor of Pharmaceutical Sciences and Chemistry

Email: lli@pharmacy.wisc.edu

David Lynn

Position title: Professor of Chemical and Biological Engineering and Chemistry

Email: dlynn@engr.wisc.edu

Jeff Martell

Position title: Assistant Professor of Chemistry

Email: jdmartell@wisc.edu

Sandro Mecozzi

Position title: Professor of Pharmaceutical Sciences and Chemistry

Email: sandro.mecozzi@wisc.edu

Monica Neugebauer

Position title: Assistant Professor

Email: meneugebauer@wisc.edu

Bio: Neugebauer, Monica E.

David C. Schwartz

Position title: Kellett Professor of Chemistry and Genetics

Email: schwartz@chem.wisc.edu

Lloyd M. Smith

Position title: W. L. Hubbell Professor of Chemistry, Hall-Fischer Professor of Chemistry

Email: smith@chem.wisc.edu

Weiping Tang

Position title: Professor of Pharmaceutical Sciences and Chemistry

Email: wtang@pharmacy.wisc.edu

Zoe Todd

Position title: Assistant Professor

Email: zrtodd@wisc.edu

Tina Wang

Position title: Assistant Professor of Chemistry

Email: twang495@wisc.edu

James C. Weisshaar

Position title: Richard J. Burke Professor of Chemistry

Email: weisshaar@chem.wisc.edu

Martin T. Zanni

Position title: V. W. Meloche-Bascom Professor of Chemistry

Email: zanni@chem.wisc.edu

Chemical Biology Labs

  • Blackwell Group

    The Blackwell Group is focused on the development of chemical strategies to manipulate bacterial cell-cell communication processes.

  • Boros Group

    The Boros Group develops metal-based molecular imaging probes and therapeutics for personalized medicine.

  • Brunold Group

    The Brunold Group investigates the geometric and electronic properties, and thus the reactivity, of metal centers in proteins and cofactors through combined spectroscopic and computational studies of key enzymatic states and synthetic inorganic model complexes.

  • Buller Group

    The Buller Group research is focussed on how to engineer new biocatalytic reactions and do so with a broad substrate scope, a major challenge in enzymology.

  • Cavagnero Group

    The Cavagnero Group focuses on understanding the early stages of protein folding and aggregation in the cell, with emphasis on the role of the ribosome, molecular chaperones and prions.

  • Coon Laboratory

    The Coon Laboratory develops and applies mass spectrometric technology to study human health.

  • Gellman Group

    The Gellman Group is focused on the design, synthesis and evaluation of new types of biopolymer-like molecules that display stable conformations and useful functions ("foldamers").

  • Goldsmith Group

    The Goldsmith Group is developing new technology for controlling how light interacts with molecules, often at the level of single molecules.

  • Huang Laboratory

    The main goal of the Huang Lab is to understand and manipulate biomolecular dynamics by developing and applying novel statistical mechanics-based methods that can bridge the gap between experiments and simulations.

  • Jin Group

    The Jin Group is interested in the chemistry, physics, and technological applications of nanoscale and solid-state materials.

  • Martell Group

    The Martell Group develops catalysts that merge the benefits of enzymes and synthetic chemistry, with applications spanning sustainable synthesis, chemical biology, and plastic recycling.

  • Schomaker Group

    The Schomaker Group specializes in synthetic organic chemistry.

  • Schwartz Laboratory

    The Schwartz Lab creates functional systems for many types of genome analysis engendering large data sets for providing scalable biological insights.

  • Smith Group

    The Smith Group is an interdisciplinary group of researchers developing new technologies to drive biological research.

  • Todd Group

    The Todd Lab's interest lies in investigating the origins of life on Earth and understanding the implications for the possibility of life on other planets.

  • Wang Group

    The Wang Group research centers around protein folding and function, and how problems in this area can cause disease, inparticular neurodegenerative disorders.

  • Zanni Group

    The Zanni Group studies topics in biophysics and the energy sciences using 2D IR spectroscopy.

  • Forest Laboratory (Affiliate)

    The Forest Lab studies biological interactions at the molecular level and is particularly interested in the structures, functions, and mechanisms of bacterial proteins with consequences to prokaryotic physiology and symbiosis with eukaryotes.

  • Ge Laboratory (Affiliate)

    The Ge Lab's research is trans-disciplinary and cuts across the traditional boundaries of chemistry, biology, and medicine.

  • Hoskins Group (Affiliate)

    The Hoskins Group uses highly multidisciplinary approach to studying eukaryotic RNA processing.

  • Li Laboratory (Affiliate)

    Research in the Li Lab focuses on developing and implementing an array of novel mass spectrometry-based strategies to answer questions about the most complex and elusive set of signaling molecules, the neuropeptides, and gain new insights into the roles that peptide hormones and neurotransmitters play in the plasticity of neural circuits and behavior.

  • Lynn Group (Affiliate)

    Lynn Group research is focused broadly on the design and synthesis of functional organic materials and the fabrication and physical characterization of polymers, macromolecular assemblies, nanoscale materials, and surfaces/interfaces.

  • Mecozzi Laboratory (Affiliate)

    The Mecozzi Lab research efforts focus on fundamental studies of non-covalent interactions and the application of the resulting findings to biochemical and biomedical problems.

  • Neugebauer Laboratory (Affiliate)

    The Neugebauer Lab is interested in the discovery, characterization, and evolution of enzymes for biocatalysis and chemical biology.

  • Rienstra Laboratory (Affiliate)

    The Rienstra Lab is interested in the development and application of solid-state NMR spectroscopy to protein, lipid and small molecule structure and dynamics.

  • Tang Laboratory (Affiliate)

    The Tang Lab focuses on drug discovery, an interdisciplinary field that involves a broad range of skill sets.

  • Weeks Group (Affiliate)

    The Weeks Group is a chemical biology lab focused on developing and applying enzymatic tools for spatially- and temporally-resolved mapping of post-translational modifications using mass spectrometry-based proteomics.