
The Mecozzi Lab’s research efforts focus on fundamental studies of non-covalent interactions and the application of the resulting findings to biochemical and biomedical problems. They use the predictive value of advanced computational techniques in conjunction with the power of chemical synthesis to generate molecules that can recognize each other through intermolecular forces. The study of these complexes allows the Mecozzi Lab to explore a variety of different chemical and biological phenomena. Current projects include the design and development of new idrophobic ionic liquids that can be used for the delivery of both hydrophobic and hydrophilic small molecule drugs as well as biologics such as monoclonal antibodies and nucleic acids. In a second project, they are developing lipid nanoparticles able to target and engineer immune cells like T and NK cells to be used in the therapy of solid tumors.