The Mecozzi Lab research efforts focus on fundamental studies of non-covalent interactions and the application of the resulting findings to biochemical and biomedical problems. They use the predictive value of advanced computational techniques in conjunction with the power of chemical synthesis to generate molecules that can recognize each other through intermolecular forces. The study of these complexes allows the Mecozzi Lab to explore a variety of different chemical and biological phenomena. These include the nature of specific intermolecular forces, the origin of the peculiar fluorous phase behavior in highly fluorinated materials, targeted drug delivery through semifluorinated functional materials, and the recognition properties of RNA.