The Golden research labs are heavily steeped in synthetic organic medicinal chemistry. We develop new and efficient synthetic chemistry methods to generate drug-like heterocycles that are developed across multiple medicinal chemistry platforms. We discovered and pioneered a quinazolinone rearrangement that has been used to generate a variety of scaffolds. This compound library is then shared with a select group of biology collaborators who screen the compounds and provide data which we use to advance compounds through drug development pipelines. The group is currently focused on several anti-infective efforts that include developing antivirals for encephalitic alphaviruses (e.g., EEEV) and arthritic alphaviruses (chikungunya), antiparasitic agents (e.g. leishmaniasis), and anti-amoebic compounds (e.g. primary amoebic meningoencephalitis).