An article written by Emeritus Professor Daniel H. Rich, a retrospective of our distinguished alumnus Emeritus Professor Ralph F. Hirschmann, Professor of Medicinal and Organic Chemistry, School of Pharmacy and Department of Chemistry, University of Wisconsin-Madison, appeared in the ACS Chemical Biology magazine. The title of the article is: “A Perspective”. The link to the ACS website is: https://pubs.acs.org/. The direct link to the article is: http://pubs.acs.org/doi/pdfplus/10.1021/cb900208u.