1315 Seminar Hall @ 12:05 pm
Exploring the connections between chelating polymer structure and rare-earth element binding thermodynamics
1315 Seminar Hall @ 12:05 pm
Exploring the connections between chelating polymer structure and rare-earth element binding thermodynamics
1315 Seminar Hall, North Tower @ 3:30 pm
Physics and Chemistry at the Nanoscale
1315 Seminar Hall @ 11:00 am
Using Vibrational Perturbation Theory to Gain Chemical Insights from Vibrational Spectra
1315 Seminar Hall @ 12:05 pm
Designing Ion-Conducting Materials for Batteries and Beyond
1315 Seminar Hall @ 12:05 pm
Mass Spectrometry Applications for Studying Ovarian Cancer
1315 Seminar Hall @ 3:30 pm - 4:30 pm
Utilizing biocatalysis and synthetic chemistry to access new natural products
1315 Seminar Hall @ 11:00 am - 12:00 pm
Molecular Electronic Structure at the Nexus of Classical and Quantum Computing
1315 Seminar Hall @ 12:05 pm - 1:00 pm
MS-Based Glycomics and Glycoproteomics Methods Enabling Better Understanding the Biological and Biomedical Roles of Glycans in Neurodegenerative Diseases
Starting in Room 2401 and moving into the North Atrium and Learning Studio @ 9:00 am - 6:30 pm
"Single Atom Logic for Skeletal Editing" Reactions which can manipulate the connectivity of the molecular skeleton are underexplored as tools for late-stage functionalization, in part because their implementation has been hindered by their often nonintuitive retrosynthetic logic. This presentation will cover selected transformations discovered in our laboratory which address this challenge by enabling single-atom changes to aliphatic and aromatic systems through the insertion and deletion of single heavy atoms (C,N,O, etc.), as well as more complex manipulations leveraging combinations of these elementary transformations. Our approach to this problem is modality-agnostic, drawing from a wide range of reactive species and synthetic disciplines, but with a significant focus on reagent design and photochemistry. Applications to late-stage functionalization and diversification of complex pharmaceutically relevant compounds as well as unique opportunities for synthesis will be presented alongside mechanistic findings.