Organic Syntheses Seminar – Prof. Josep Cornella (Max-Planck-Institut für Kohlenforschung)

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1315 Seminar Hall, North Tower
@ 3:30 pm

Prof. Josep Cornella

Title: Tales on Bismuth Catalysis

Abstract: The ability of the bismuth (Bi) to maneuver between different oxidation states in a catalytic redox cycle will be presented.1-7 We will show how Bi challenges the current dogmas of catalysis by emulating canonical organometallic steps of transition metals. A series of Bi complexes capable of revolving between oxidation states Bi(I)/Bi(III) and Bi(III)/Bi(V) have been unlocked and applied in various contexts of catalysis for organic synthesis. For example, capitalizing on the Bi(III)/Bi(V) redox pair, we have developed a catalytic protocol for the C‒F, C‒O and C‒N bond formation. Additionally, we will show how a low-valent redox manifold based on Bi(I)/Bi(III) has been applied in the reduction of hydrazines and nitro compounds, the decomposition of inert N2O and SF6 and the catalytic hydrodefluorination of C(sp2)‒F bonds. In addition, we will show how one-electron pathways are also accessible, thus providing a platform for SET processes capitalizing on the triad Bi(I)/Bi(II)/Bi(III) for organic synthesis. For all methodologies, a combination of rational ligand design with an in depth analysis of all the elementary steps proved crucial to unlock the catalytic properties of such an intriguing element of the periodic table.

Link to Bio

Keywords: Organic chemistry, organometallic chemistry, catalysis

Host: Prof. Zach Wickens