Publications: Sandro Mecozzi

Wang, J. X.; Drelich, A. J.; Hopkins, C. M.; Mecozzi, S.; Li, L. J.; Kwon, G.; Hong, S., Gold nanoparticles in virus detection: Recent advances and potential considerations for SARS-CoV-2 testing development. Wiley Interdisciplinary Reviews-Nanomedicine and Nanobiotechnology 2021, e1754. 10.1002/wnan.1754

Padilla, M. S.; Bertz, C.; Berdusco, N.; Mecozzi, S., Expanding the structural diversity of hydrophobic ionic liquids: physicochemical properties and toxicity of Gemini ionic liquids. Green Chem. 2021. 10.1039/d1gc00742d

Esson, M. M.; Mecozzi, S., Preparation, Characterization, and Formulation Optimization of Ionic-Liquid-in-Water Nanoemulsions toward Systemic Delivery of Amphotericin B. Molecular pharmaceutics 2020, 17 (6), 2221-2226. 10.1021/acs.molpharmaceut.9b00809

Barres, A. R.; Molugu, S. K.; Stewart, P. L.; Mecozzi, S., Droplet Core Intermolecular Interactions and Block Copolymer Composition Heavily Influence Oil-In-Water Nanoemulsion Stability. Langmuir 2019, 35 (39), 12765-12772. 10.1021/acs.langmuir.9b01519

Barres, A. R.; Wimmer, M. R.; Mecozzi, S., Multicompartment Theranostic Nanoemulsions Stabilized by a Triphilic Semifluorinated Block Copolymer. Molecular pharmaceutics 2017, 14 (11), 3916-3926. 10.1021/acs.molpharmaceut.7b00624

Parks, C. L.; Tucker, W.; Amlong, C. A.; Mecozzi, S.; Pearce, R. A., Lipid-free Fluoropolymer-based Propofol Emulsions and Lipid Reversal of Propofol Anesthesia in Rats. Anesthesiology 2016, 124 (6), 1328-1337. 10.1097/aln.0000000000001080

Fleetwood, M. C.; McCoy, A. M.; Mecozzi, S., Synthesis and characterization of environmentally benign, semifluorinated polymers and their applications in drug delivery. J. Fluorine Chem. 2016, 190, 75-80. 10.1016/j.jfluchem.2016.09.001

Razgulin, A. V.; Mecozzi, S., Synthesis, emulsification and self-assembly properties of sugar-containing semifluorinated amphiphiles. Carbohydr. Res. 2015, 406, 10-18. 10.1016/j.carres.2014.12.009

Tucker, W. B.; McCoy, A. M.; Fix, S. M.; Stagg, M. F.; Murphy, M. M.; Mecozzi, S., Synthesis, Physicochemical Characterization, and Self-Assembly of Linear, Dibranched, and Miktoarm Semifluorinated Triphilic Polymers. Journal of Polymer Science Part a-Polymer Chemistry 2014, 52 (23), 3324-3336. 10.1002/pola.27394

Decato, S.; Bemis, T.; Madsen, E.; Mecozzi, S., Synthesis and characterization of perfluoro-tert-butyl semifluorinated amphiphilic polymers and their potential application in hydrophobic drug delivery. Polymer Chemistry 2014, 5 (22), 6461-6471.

Tucker, W. B.; Mecozzi, S., Base-induced instability of fluorotelomer alcohols. J. Fluorine Chem. 2013, 156, 26-29. 10.1016/j.jfluchem.2013.08.010

Parks, C. L.; Simmons, K. T.; Brunner, K. G.; Mecozzi, S.; Pearce, R. A.; Lopukhin, S., DELIVERY OF INTRAVENOUS SEVOFLURANE BY FLUOROUS EMULSION FOR ANESTHESIA IN RHESUS MACAQUES. Anesth. Analg. 2013, 116, 30-30.

Simmons, K.; Nejati, E.; Johnson, R.; Pearce, R.; Albrecht, R.; Mecozzi, S., Investigation of Hypersensitivity to PEGylated Particles For Use in Drug Delivery. FASEB J. 2012, 26.

Jee, J. P.; Parlato, M. C.; Perkins, M. G.; Mecozzi, S.; Pearce, R. A., Exceptionally Stable Fluorous Emulsions for the Intravenous Delivery of Volatile General Anesthetics. Anesthesiology 2012, 116 (3), 580-585. 10.1097/ALN.0b013e3182475d4d

Jee, J. P.; McCoy, A.; Mecozzi, S., Encapsulation and Release of Amphotericin B from an ABC Triblock Fluorous Copolymer. Pharm. Res. 2012, 29 (1), 69-82. 10.1007/s11095-011-0511-9

Biller, M. J.; Mecozzi, S., A high level computational study of the CH4/CF4 dimer: how does it compare with the CH4/CH4 and CF4/CF4 dimers? Mol. Phys. 2012, 110 (7), 377-387. 10.1080/00268976.2011.648961

Parlato, M. C.; Jee, J. P.; Teshite, M.; Mecozzi, S., Synthesis, Characterization, and Applications of Hemifluorinated Dibranched Amphiphiles. J. Org. Chem. 2011, 76 (16), 6584-6591. 10.1021/jo200835y

Johnson, R. A.; Simmons, K. T.; Fast, J. P.; Schroeder, C. A.; Pearce, R. A.; Albrecht, R. M.; Mecozzi, S., Histamine Release Associated with Intravenous Delivery of a Fluorocarbon-Based Sevoflurane Emulsion in Canines. J. Pharm. Sci. 2011, 100 (7), 2685-2692. 10.1002/jps.22488

Fast, J. P.; Perkins, M. G.; Pearce, R. A.; Mecozzi, S., Fluoropolymer-based emulsions for the intravenous delivery of sevoflurane. Anesthesiology 2008, 109 (4), 651-656.

Slaughter, J. N.; Schmidt, K. M.; Byram, J. L.; Mecozzi, S., Synthesis and self-assembly properties of a novel poly(ethylene glycol) -fluorocarbon-phospholipid triblock copolymer. Tetrahedron Lett. 2007, 48 (22), 3879-3882. 10.1016/j.tetlet.2007.03.148

Martin, O. M.; Mecozzi, S., Synthesis and pH-dependent self-assembly of semifluorinated calix 4 arenes. Tetrahedron 2007, 63 (25), 5539-5547. 10.1016/j.tet.2007.04.030

Anderson, P. C.; Mecozzi, S., Minimum sequence requirements for the binding for paromomycin to the rDNA decoding site A. Biopolymers 2007, 86 (2), 95-111. 10.1002/bip.20707

Woll, M. G.; Hadley, E. B.; Mecozzi, S.; Gellman, S. H., Stabilizing and destabilizing effects of phenylalanine -> F-5-phenylalanine mutations on the folding of a small protein. Journal of the American Chemical Society 2006, 128 (50), 15932-15933. 10.1021/ja0634573

Razgulin, A. V.; Mecozzi, S., Binding properties of aromatic carbon-bound fluorine. J. Med. Chem. 2006, 49 (26), 7902-7906. 10.1021/jm0600702

Anderson, P. C.; Mecozzi, S., Minimum sequence requirements for selective RNA-ligand binding: A molecular mechanics algorithm using molecular dynamics and free-energy techniques. J. Comput. Chem. 2006, 27 (14), 1631-1640. 10.1002/jcc.20459

Martin, O. M.; Yu, L.; Mecozzi, S., Solution self-assembly and solid state properties of fluorinated amphiphilic calix 4 arenes. Chemical Communications 2005, (39), 4964-4966. 10.1039/b506781b

Martin, O. M.; Mecozzi, S., Synthesis and self-assembly of amphiphilic semifluorinated calix 4 arenes. Supramolecular Chemistry 2005, 17 (1-2), 9-15. 10.1080/10610270412331328998

Anderson, P. C.; Mecozzi, S., Unusually short RNA sequences: Design of a 13-mer RNA that selectively binds and recognizes theophylline. Journal of the American Chemical Society 2005, 127 (15), 5290-5291. 10.1021/ja0432463

Anderson, P. C.; Mecozzi, S., Identification of a 14mer RNA that recognizes and binds flavin mononucleotide with high affinity. Nucleic Acids Res. 2005, 33 (22), 6992-6999. 10.1093/nar/gki992

Hoang, K. C.; Mecozzi, S., Aqueous solubilization of highly fluorinated molecules by semifluorinated surfactants. Langmuir 2004, 20 (18), 7347-7350. 10.1021/la049128a

Ngola, S. M.; Kearney, P. C.; Mecozzi, S.; Russell, K.; Dougherty, D. A., A selective receptor for arginine derivatives in aqueous media. Energetic consequences of salt bridges that are highly exposed to water. Journal of the American Chemical Society 1999, 121 (6), 1192-1201. 10.1021/ja982499r

West, A. P.; Mecozzi, S.; Dougherty, D. A., Theoretical studies of the supramolecular synthon benzene … hexafluorobenzene. J. Phys. Org. Chem. 1997, 10 (5), 347-350. 10.1002/(sici)1099-1395(199705)10:5<347::aid-poc893>;2-x

Mecozzi, S.; West, A. P.; Dougherty, D. A., Cation-pi interactions in aromatics of biological and medicinal interest: Electrostatic potential surfaces as a useful qualitative guide. Proc. Natl. Acad. Sci. U. S. A. 1996, 93 (20), 10566-10571. 10.1073/pnas.93.20.10566

Mecozzi, S.; West, A. P.; Dougherty, D. A., Cation-pi interactions in simple aromatics: Electrostatics provide a predictive tool. Journal of the American Chemical Society 1996, 118 (9), 2307-2308. 10.1021/ja9539608

Bonini, C.; Bianco, A.; Difabio, R.; Mecozzi, S.; Proposito, A.; Righi, G., Studies on the Diastereoselective Reduction of Beta-Hydroxy Ketones to 1,3-Diols with Common Hydride Reagents. Gazz. Chim. Ital. 1991, 121 (2), 75-80.

Bonini, C.; Difabio, R.; Mecozzi, S.; Righi, G., One Pot Cyclization of Epoxyolefins to Substituted Cycloalkanols Via Free-Radicals. Tetrahedron Lett. 1990, 31 (37), 5369-5372. 10.1016/s0040-4039(00)98074-2

Bonadies, F.; Difabio, R.; Gubbiotti, A.; Mecozzi, S.; Bonini, C., STUDIES ON ASYMMETRIC-SYNTHESIS OF BETA-HYDROXY-DELTA-LACTONE INHIBITORS OF HMGCOA REDUCTASE .1. A NEW PREPARATION OF THE LACTONE MOIETY OF COMPACTIN. Tetrahedron Lett. 1987, 28 (6), 703-706. 10.1016/s0040-4039(00)95819-2