Experiment 14: Suzuki Coupling

Suzuki Coupling

Due Dates:

3-May/4-May A/B

 

Chemical Safety Information:

Reagents, Products, and Solvents
p-tolueneboronic acid (4-methoxyphenyl)-boronic acid p-bromo-anisole
p-bromo-toluene deuterated chloroform 1-(4-bromophenyl)-acetophenone
ethanol dichloromethane Pd atomic absorption standard
potassium hydroxide magnesium sulfate

 

Experimental Spectra:

Sample 1H-NMR Suzuki Coupling Products (not available for submission for credit)

Stock FID 1H-NMR Suzuki A1 (available for submission for credit, see laboratory manual for details)

Stock FID 1H-NMR Suzuki A2 (available for submission for credit, see laboratory manual for details)

Stock FID 1H-NMR Suzuki A3 (available for submission for credit, see laboratory manual for details)

Stock FID 1H-NMR Suzuki B1 (available for submission for credit, see laboratory manual for details)

Stock FID 1H-NMR Suzuki B2 (available for submission for credit, see laboratory manual for details)

Stock FID 1H-NMR Suzuki B3 (available for submission for credit, see laboratory manual for details)

 

Supplemental Readings:

The 2010 Nobel Prize in Chemistry: Palladium-Catalysed Cross-Coupling

Information for the Public on the Nobel Prize in Chemistry 2010

Scientific Background on the Nobel Prize in Chemistry 2010