Organic Chemistry Seminar – Prof. Andy McNally, Colorado State University
October 20 @ 3:30 pm - 4:30 pm
Prof. Andy McNally
Colorado State University
Organic Chemistry Seminar
“Selective Functionalization of Pyridines and Diazines via Heterocyclic Phosphonium Salts”
Selective methods that can functionalize electron-deficient heterocycles are in great demand due to their prevalence in biologically active compounds. Pyridines and diazines, in particular, are widespread components of pharmaceutical compounds yet methods to transform these motifs into valuable derivatives are still greatly sought after. We will present a selection of catalytic and non-catalytic methods using phosphorus intermediates that enable multiple new bond-constructions on these heterocycles. A particular emphasis will be placed on phosphorus ligand-coupling reactions that represent an alternative means to form C–C and C-Heteroatom bonds.
For more information contact: Mary Hanson at email@example.com