All Faculty and Research Staff Publications

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Fuchs SM, Raines RT. Arginine grafting to endow cell permeability. ACS Chemical Biology. 2007 ;2:167-170.
Kalia J, Raines RT. Catalysis of imido group hydrolysis in a maleimide conjugate. Bioorganic & Medicinal Chemistry Letters. 2007 ;17:6286-6289.
Johnson JR, Chao T-Y, Lavis LD, Raines RT. Cytotoxic ribonucleases: The dichotomy of coulombic forces. Biochemistry. 2007 ;46:10308-10316.
Kalia J, Abbott NL, Raines RT. General method for site-specific protein immobilization by staudinger ligation. Bioconjugate Chemistry. 2007 ;18:1064-1069.
Johnson JR, Lin SR, Raines RT. Genetic selection reveals the role of a buried, conserved polar residue. Protein Science. 2007 ;16:1609-1616.
Horng J-C, Kotch FW, Raines RT. Is glycine a surrogate for a D-amino acid in the collagen triple helix?. Protein Science. 2007 ;16:208-215.
Fuchs SM, Rutkoski TJ, Kung VM, Groeschl RT, Raines RT. Increasing the potency of a cytotoxin with an arginine graft. Protein Engineering Design & Selection. 2007 ;20:505-509.
Johnson JR, McCoy JG, Bingman CA, Phillips, Jr. GN, Raines RT. Inhibition of human pancreatic ribonuclease by the human ribonuclease inhibitor protein. Journal of Molecular Biology. 2007 ;368:434-449.
Johnson JR, Lavis LD, Raines RT. Intraspecies regulation of ribonucleolytic activity. Biochemistry. 2007 ;46:13131-13140.
Shoulders MD, Raines RT. Modulating collagen triple helix stability with 4-chloro-, 4-fluoro-, and 4-methylprolines. Biopolymers. 2007 ;88:593-593.
Jewell CM, Fuchs SM, Flessner RM, Raines RT, Lynn DM. Multilayered films fabricated from an oligoarginine-conjugated protein promote efficient surface-mediated protein transduction. Biomacromolecules. 2007 ;8:857-863.
Binder JB, Blank JJ, Raines RT. Olefin metathesis in homogenous aqueous media catalyzed by conventional ruthenium catalysts. Organic Letters. 2007 ;9:4885-4888.
Tam A, Arnold U, Soellner MB, Raines RT. Protein prosthesis: 1,5-disubstituted[1,2,3]triazoles as cis-peptide bond surrogates. Journal of the American Chemical Society. 2007 ;129:12670-+.
Binder JB, Guzei IA, Raines RT. Salicylaldimine ruthenium alkylidene complexes: Metathesis catalysts tuned for protic solvents. Advanced Synthesis & Catalysis. 2007 ;349:395-404.
Lavis LD, Rutkoski TJ, Raines RT. Tuning the pK(a) of fluorescein to optimize binding assays. Analytical Chemistry. 2007 ;79:6775-6782.
Govindaraju T, Bertics PJ, Raines RT, Abbott NL. Using measurements of anchoring energies of liquid crystals on surfaces to quantify proteins captured by immobilized ligands. Journal of the American Chemical Society. 2007 ;129:11223-11231.
Tam A, Soellner MB, Raines RT. Water-soluble phosphinothiols for traceless Staudinger ligation and integration with expressed protein ligation. Journal of the American Chemical Society. 2007 ;129:11421-11430.
Raines RT. 2005 Emil Thomas Kaiser Award. Protein Science. 2006 ;15:1219-1225.
Liu XS, Jang CH, Zheng F, Jurgensen A, Denlinger JD, Dickson KA, Raines RT, Abbott NL, Himpsel FJ. Characterization of protein immobilization at silver surfaces by near edge X-ray absorption fine structure spectroscopy. Langmuir. 2006 ;22:7719.
Allen MJ, Raines RT, Kiessling LL. Contrast agents for magnetic resonance imaging synthesized with ring-opening metathesis polymerization. Journal of the American Chemical Society. 2006 ;128:6534-6535.
Hodges JA, Raines RT. Energetics of an n ->pi* interaction that impacts protein structure. Organic Letters. 2006 ;8:4695.
Lavis LD, Chao TY, Raines RT. Fluorogenic label for biomolecular imaging. ACS Chemical Biology. 2006 ;1:252.
Smith BD, Raines RT. Genetic selection for critical residues in ribonucleases. Journal of Molecular Biology. 2006 ;362:459.
Fuchs SM, Raines RT. Internalization of cationic peptides: the road less (or more?) traveled. Cellular and Molecular Life Sciences. 2006 ;63:1819.
Lavis LD, Chao TY, Raines RT. Latent blue and red fluorophores based on the trimethyl lock. Chembiochem. 2006 ;7:1151.
Horng JC, Hawk AJ, Zhao Q, Benedict ES, Burke SD, Raines RT. Macrocyclic scaffold for the collagen triple helix. Organic Letters. 2006 ;8:4735.
Kalia J, Raines RT. Reactivity of intein thioesters: Appending a functional group to a protein. Chembiochem. 2006 ;7:1375.
Shoulders MD, Hodges JA, Raines RT. Reciprocity of steric and stereoelectronic effects in the collagen triple helix. Journal of the American Chemical Society. 2006 ;128:8112.
Johnson RJ, Lin SR, Raines RT. A ribonuclease zymogen activated by the NS3 protease of the hepatitis C virus. FEBS Journal. 2006 ;273:5457.
Kotch FW, Raines RT. Self-assembly of synthetic collagen triple helices. Proceedings of the National Academy of Sciences of the United States of America. 2006 ;103:3028-3033.
Eckenroth B, Harris K, Turanov AA, Gladyshev VN, Raines RT, Hondal RJ. Semisynthesis and characterization of mammalian thioredoxin reductase. Biochemistry. 2006 ;45:5158-5170.
Soellner MB, Tam A, Raines RT. Staudinger ligation of peptides at non-glycyl residues. Journal of Organic Chemistry. 2006 ;71:9824-9830.
Horng JC, Raines RT. Stereoelectronic effects on polyproline conformation. Protein Science. 2006 ;15:74-83.
Kiessling LL, Wedde SG, Raines RT. Symbiosis: Chemical biology at Wisconsin. ACS Chemical Biology. 2006 ;1:481-484.
Jenkins CL, Thiyagarajan N, Sweeney RY, Guy MP, Kelemen BR, Acharya KR, Raines RT. Binding of non-natural 3 '-nucleotides to ribonuclease A. FEBS Journal. 2005 ;272:744-755.
Kersteen EA, Barrows SR, Raines RT. Catalysis of protein disulfide bond isomerization in a homogeneous substrate. Biochemistry. 2005 ;44:12168-12178.
Nilsson BL, Soellner MB, Raines RT. Chemical synthesis of proteins [Review]. Annual Review of Biophysics & Biomolecular Structure. 2005 ;34:91-118.
Lee JE, Raines RT. Cytotoxicity of bovine seminal ribonuclease: Monomer versus dimer. Biochemistry. 2005 ;44:15760-15767.
Chandran SS, Dickson KA, Raines RT. Latent fluorophore based on the trimethyl lock. Journal of the American Chemical Society. 2005 ;127:1652-1653.
Jenkins CL, McCloskey AI, Guzei IA, Eberhardt ES, Raines RT. O-acylation of hydroxyproline residues: Effect on peptide-bond isomerization and collagen stability. Biopolymers. 2005 ;80:1-8.
Jenkins CL, Vasbinder MM, Miller SJ, Raines RT. Peptide bond isosteres: Ester or (E)-alkene in the backbone of the collagen triple helix. Organic Letters. 2005 ;7:2619-2622.
Fuchs SM, Raines RT. Polyarginine as a multifunctional fusion tag. Protein Science. 2005 ;14:1538-1544.
Miller BG, Raines RT. Reconstitution of a defunct glycolytic pathway via recruitment of ambiguous sugar kinases. Biochemistry. 2005 ;44:10776-10783.
Dickson KA, Haigis MC, Raines RT. Ribonuclease inhibitor: Structure and function [Review]. Progress in Nucleic Acid Research and Molecular Biology. 2005 ;80:349-+.
Hodges JA, Raines RT. Stereoelectronic and steric effects in the collagen triple helix: Toward a code for strand association. Journal of the American Chemical Society. 2005 ;127:15923-15932.
Smith BD, Soellner MB, Raines RT. Synthetic surfaces for ribonuclease adsorption. Langmuir. 2005 ;21:187-190.