All Faculty and Research Staff Publications

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Shoulders MD, Kotch FW, Choudhary A, Guzei IA, Raines RT. The Aberrance of the 4S Diastereomer of 4-Hydroxyproline. Journal of the American Chemical Society. 2010 ;132:10857-10865.
Kalia J, Raines RT. Advances in Bioconjugation. Current Organic Chemistry. 2010 ;14:138-147.
Rutkoski TJ, Kink JA, Strong LE, Schilling CI, Raines RT. Antitumor Activity of Ribonuclease Multimers Created by Site-Specific Covalent Tethering. Bioconjugate Chemistry. 2010 ;21:1691-1702.
Martin LJ, Raines RT. Carpe Diubiquitin. Angewandte Chemie-International Edition. 2010 ;49:9042-9044.
Chao T-Y, Lavis LD, Raines RT. Cellular Uptake of Ribonuclease A Relies on Anionic Glycans. Biochemistry. 2010 ;49:10666-10673.
Binder JB, Raines RT. Fermentable sugars by chemical hydrolysis of biomass. Proceedings of the National Academy of Sciences of the United States of America. 2010 ;107:4516-4521.
Binder JB, Cefali AV, Blank JJ, Raines RT. Mechanistic insights on the conversion of sugars into 5-hydroxymethylfurfural. Energy & Environmental Science. 2010 ;3:765-771.
Choudhary A, Fry CG, Raines RT. Modulation of an n ->pi* interaction with alpha-fluoro groups. Arkivoc. 2010 :251-262.
Bartlett GJ, Choudhary A, Raines RT, Woolfson DN. n ->pi* interactions in proteins. Nature Chemical Biology. 2010 ;6:615-620.
Jakobsche CE, Choudhary A, Miller SJ, Raines RT. n -> pi(star) Interaction and n)(pi Pauli Repulsion Are Antagonistic for Protein Stability. Journal of the American Chemical Society. 2010 ;132:6651-+.
Krow GR, Liu N, Sender M, Lin G, Centafont R, Sonnet PE, De Brosse C, Ross, Charles W. III, Carroll PJ, Shoulders MD, et al. Oligomers of a 5-Carboxy-methanopyrrolidine beta-Amino Acid. A Search for Order. Organic Letters. 2010 ;12:5438-5441.
Gorres KL, Raines RT. Prolyl 4-hydroxylase. Critical Reviews in Biochemistry and Molecular Biology. 2010 ;45:106-124.
Shoulders MD, Satyshur KA, Forest KT, Raines RT. Stereoelectronic and steric effects in side chains preorganize a protein main chain. Proceedings of the National Academy of Sciences of the United States of America. 2010 ;107:559-564.
Choudhary A, Kamer KJ, Powner MW, Sutherland JD, Raines RT. A Stereoelectronic Effect in Prebiotic Nucleotide Synthesis. ACS Chemical Biology. 2010 ;5:655-657.
Binder JB, Blank JJ, Cefali AV, Raines RT. Synthesis of Furfural from Xylose and Xylan. Chemsuschem. 2010 ;3:1268-1272.
Krow GR, Edupuganti R, Gandla D, Choudhary A, Lin GL, Sonnet PE, DeBrosse C, Ross CW, Cannon KC, Raines RT. 5(6)-anti-Substituted-2-azabicyclo[2.1.1]hexanes: A Nucleophilic Displacement Route. Journal of Organic Chemistry. 2009 ;74:8232-8242.
Shoulders MD, Raines RT. Collagen Structure and Stability. Annual Review of Biochemistry. 2009 ;78:929-958.
Tam A, Raines RT. Coulombic effects on the traceless Staudinger ligation in water. Bioorganic & Medicinal Chemistry. 2009 ;17:1055-1063.
Gorres KL, Raines RT. Direct and continuous assay for prolyl 4-hydroxylase. Analytical Biochemistry. 2009 ;386:181-185.
Watkins RW, Lavis LD, Kung VM, Los GV, Raines RT. Fluorogenic affinity label for the facile, rapid imaging of proteins in live cells. Organic & Biomolecular Chemistry. 2009 ;7:3969-3975.
Shoulders MD, Raines RT. Modulating Collagen Triple-Helix Stability with 4-Chloro, 4-Fluoro, and 4-Methylprolines. Peptides for Youth. 2009 ;611:251-252.
Choudhary A, Gandla D, Krow GR, Raines RT. Nature of Amide Carbonyl-Carbonyl Interactions in Proteins. Journal of the American Chemical Society. 2009 ;131:7244-+.
Turcotte RF, Lavis LD, Raines RT. Onconase cytotoxicity relies on the distribution of its positive charge. FEBS Journal. 2009 ;276:4270-4281.
Shoulders MD, Kamer KJ, Raines RT. Origin of the stability conferred upon collagen by fluorination. Bioorganic & Medicinal Chemistry Letters. 2009 ;19:3859-3862.
Myers EL, Raines RT. A Phosphine-Mediated Conversion of Azides into Diazo Compounds. Angewandte Chemie-International Edition. 2009 ;48:2359-2363.
Tam A, Raines RT. Protein Engineering with the Traceless Staudinger Ligation. Methods in Enzymology. 2009 ;462:25-44.
Allen MJ, Wangkanont K, Raines RT, Kiessling LL. ROMP from ROMP: A New Approach to Graft Copolymer Synthesis. Macromolecules. 2009 ;42:4023-4027.
Dickson KA, Raines RT. Silencing an Inhibitor Unleashes a Cytotoxic Enzyme. Biochemistry. 2009 ;48:5051-5053.
Binder JB, Raines RT. Simple Chemical Transformation of Lignocellulosic Biomass into Furans for Fuels and Chemicals. Journal of the American Chemical Society. 2009 ;131:1979-1985.
Derewenda U, Boczek T, Gorres KL, Yu M, Hung LW, Cooper D, Joachimiak A, Raines RT, Derewenda ZS. Structure and Function of Bacillus subtilis YphP, a Prokaryotic Disulfide Isomerase with a CXC Catalytic Motif. Biochemistry. 2009 ;48:8664-8671.
Shoulders MD, Guzei IA, Raines RT. 4-chloroprolines: Synthesis, conformational analysis, and effect on the collagen triple helix. Biopolymers. 2008 ;89:443-454.
Lavis LD, Raines RT. Bright ideas for chemical biology. ACS Chemical Biology. 2008 ;3:142-155.
Gorres KL, Edupuganti R, Krow GR, Raines RT. Conformational preferences of substrates for human prolyl 4-hydroxylase. Biochemistry. 2008 ;47:9447-9455.
Turcotte RF, Raines RT. Design and Characterization of an HIV-Specific Ribonuclease Zymogen. AIDS Research and Human Retroviruses. 2008 ;24:1357-1363.
Tam A, Soellner MB, Raines RT. Electronic and steric effects on the rate of the traceless Staudinger ligation. Organic & Biomolecular Chemistry. 2008 ;6:1173-1175.
Rutkoski TJ, Raines RT. Evasion of ribonuclease inhibitor as a determinant of ribonuclease cytotoxicity. Current Pharmaceutical Biotechnology. 2008 ;9:185-199.
Smith BD, Raines RT. Genetic selection for peptide inhibitors of angiogenin. Protein Engineering Design & Selection. 2008 ;21:289-294.
Yatzeck MM, Lavis LD, Chao TY, Chandran SS, Raines RT. A highly sensitive fluorogenic probe for cytochrome P450 activity in live cells. Bioorganic & Medicinal Chemistry Letters. 2008 ;18:5864-5866.
Kalia J, Raines RT. Hydrolytic stability of hydrazones and oximes. Angewandte Chemie-International Edition. 2008 ;47:7523-7526.
Turcotte RF, Raines RT. Interaction of onconase with the human ribonuclease inhibitor protein. Biochemical and Biophysical Research Communications. 2008 ;377:512-514.
Raines RT. Jeremy R. Knowles (1935-2006). ACS Chemical Biology. 2008 ;3:262-264.
Binder JB, Raines RT. Olefin metathesis for chemical biology. Current Opinion in Chemical Biology. 2008 ;12:767-773.
Wennemers H, Raines RT. Peptides and peptidomimetics as prototypes Editorial overview. Current Opinion in Chemical Biology. 2008 ;12:690-691.
Chorghade MS, Mohapatra DK, Sahoo G, Gurjar MK, Mandlecha MV, Bhoite N, Moghe S, Raines RT. Practical syntheses of 4-fluoroprolines. Journal of Fluorine Chemistry. 2008 ;129:781-784.
Lee EJ, Raines RT. Ribonucleases as novel chemotherapeutics - The ranpirnase example. Biodrugs. 2008 ;22:53-58.
Gottlieb D, Morin SA, Jin S, Raines RT. Self-assembled collagen-like peptide fibers as templates for metallic nanowires. Journal of Materials Chemistry. 2008 ;18:3865-3870.
Kotch FW, Guzei IA, Raines RT. Stabilization of the collagen triple helix by O-methylation of hydroxyproline residues. Journal of the American Chemical Society. 2008 ;130:2952-2953.
Lee EJ, Bae E, Bingman CA, Phillips, Jr. GN, Raines RT. Structural basis for catalysis by onconase. Journal of Molecular Biology. 2008 ;375:165-177.