All Faculty and Research Staff Publications

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Schienebeck CM, Li XX, Shu XZ, Tang WP. 3-Acyloxy-1,4-enyne: A new five-carbon synthon for rhodium-catalyzed 5+2 cycloadditions. Pure and Applied Chemistry. 2014 ;86:409-417.
Zheng SQ, Schienebeck CM, Zhang W, Wang HY, Tang WP. Cinchona Alkaloids as Organocatalysts in Enantioselective Halofunctionalization of Alkenes and Alkynes. Asian Journal of Organic Chemistry. 2014 ;3:366-376.
Li H, Li XX, Wang HY, Winston-McPherson GN, Geng HMJ, Guzei IA, Tang WP. Copper-catalyzed tandem annulation/arylation for the synthesis of diindolylmethanes from propargylic alcohols. Chemical Communications. 2014 ;50:12293-12296.
Han LQ, Wang L, Hou XB, Fu HS, Song WG, Tang WP, Fang H. Design, synthesis and preliminary bioactivity studies of 1,2-dihydrobenzo d isothiazol-3-one-1,1-dioxide hydroxamic acid derivatives as novel histone deacetylase inhibitors. Bioorganic & Medicinal Chemistry. 2014 ;22:1529-1538.
Wang JH, Sun FE, Han LQ, Hou XB, Pan XL, Liu RS, Tang WP, Fang H. Design, synthesis, and preliminary bioactivity studies of substituted purine hydroxamic acid derivatives as novel histone deacetylase (HDAC) inhibitors. Medchemcomm. 2014 ;5:1887-1891.
Guan P, Wang L, Hou XB, Wan YC, Xu WF, Tang WP, Fang H. Improved antiproliferative activity of 1,3,4-thiadiazole-containing histone deacetylase (HDAC) inhibitors by introduction of the heteroaromatic surface recognition motif. Bioorganic & Medicinal Chemistry. 2014 ;22:5766-5775.
Wang HY, Zhang W, Schienebeck CM, Bennett SR, Tang WP. Intermolecular bromoesterification of conjugated enynes: an efficient synthesis of bromoallenes. Organic Chemistry Frontiers. 2014 ;1:386-390.
Winston-McPherson GN, Shu DX, Tang WP. Synthesis and biological evaluation of 2,3 '-diindolylmethanes as agonists of aryl hydrocarbon receptor. Bioorganic & Medicinal Chemistry Letters. 2014 ;24:4023-4025.
Liu N, Song WZ, Schienebeck CM, Zhang M, Tang WP. Synthesis of naturally occurring tropones and tropolones. Tetrahedron. 2014 ;70:9281-9305.
Fass DM, Reis SA, Ghosh B, Hennig KM, Joseph NF, Zhao WN, Nieland TJF, Guan JS, Kuhnle CEG, Tang WP, et al. Crebinostat: A novel cognitive enhancer that inhibits histone deacetylase activity and modulates chromatin-mediated neuroplasticity. Neuropharmacology. 2013 ;64:81-96.
Schienebeck CM, Robichaux PJ, Li XX, Chen LQ, Tang WP. Effect of ester on rhodium-catalyzed intermolecular 5+2 cycloaddition of 3-acyloxy-1,4-enynes and alkynes. Chemical Communications. 2013 ;49:2616-2618.
Zheng J, Xu CM, Guo J, Wei Y, Ge HJ, Li XC, Zhang CL, Jiang HJ, Pan L, Tang WP, et al. Effective Noninvasive Zygosity Determination by Maternal Plasma Target Region Sequencing. Plos One. 2013 ;8.
Zhang W, Liu N, Schienebeck CM, Zhou X, , Guzei IA, Tang WP. Enantioselective intermolecular bromoesterification of allylic sulfonamides. Chemical Science. 2013 ;4:2652-2656.
Liu RH, Winston-McPherson GN, Yang ZY, Zhou X, Song WZ, Guzei IA, Xu XF, Tang WP. Generation of Rhodium(I) Carbenes from Ynamides and Their Reactions with Alkynes and Alkenes. Journal of the American Chemical Society. 2013 ;135:8201-8204.
Shu DX, Winston-McPherson GN, Song WZ, Tang WP. Platinum-Catalyzed Tandem Indole Annulation/Arylation for the Synthesis of Diindolylmethanes and Indolo 3,2-b carbazoles. Organic Letters. 2013 ;15:4162-4165.
Xu XF, Liu P, Shu XZ, Tang WP, Houk KN. Rh-Catalyzed (5+2) Cycloadditions of 3-Acyloxy-1,4-enynes and Alkynes: Computational Study of Mechanism, Reactivity, and Regioselectivity. Journal of the American Chemical Society. 2013 ;135:9271-9274.
Shu DX, Song WZ, Li XX, Tang WP. Rhodium- and Platinum-Catalyzed 4+3 Cycloaddition with Concomitant Indole Annulation: Synthesis of Cyclohepta b indoles. Angewandte Chemie-International Edition. 2013 ;52:3237-3240.
Xu HD, Zhang RW, Li XX, Huang SY, Tang WP, Hu WH. Rhodium-Catalyzed Chemo- and Regioselective Cross-Dimerization of Two Terminal Alkynes. Organic Letters. 2013 ;15:840-843.
Li XX, Song WZ, Tang WP. Rhodium-Catalyzed Tandem Annulation and (5+1) Cycloaddition: 3-Hydroxy-1,4-enyne as the 5-Carbon Component. Journal of the American Chemical Society. 2013 ;135:16797-16800.
Liu RH, Zhang M, Winston-McPherson G, Tang WP. Ring expansion of alkynyl cyclopropanes to highly substituted cyclobutenes via a N-sulfonyl-1,2,3-triazole intermediate. Chemical Communications. 2013 ;49:4376-4378.
Liu N, Wang HY, Zhang W, Jia ZH, Guzei IA, Xu HD, Tang WP. Stereoselective Halocyclization of Alkenes With N-Acyl Hemiaminal Nucleophiles. Chirality. 2013 ;25:805-809.
Zhang M, Liu N, Tang WP. Stereoselective Total Synthesis of Hainanolidol and Harringtonolide via Oxidopyrylium-Based 5+2 Cycloaddition. Journal of the American Chemical Society. 2013 ;135:12434-12438.
Jarecki BW, Zheng SQ, Zhang LL, Li XX, Zhou X, Cui Q, Tang WP, Chanda B. Tethered Spectroscopic Probes Estimate Dynamic Distances with Subnanometer Resolution in Voltage-Dependent Potassium Channels. Biophysical Journal. 2013 ;105:2724-2732.
Shu XZ, Schienebeck CM, Song WZ, Guzei IA, Tang WP. Transfer of Chirality in the Rhodium-Catalyzed Intramolecular 5+2 Cycloaddition of 3-Acyloxy-1,4-enynes (ACEs) and Alkynes: Synthesis of Enantioenriched Bicyclo 5.3.0 decatrienes. Angewandte Chemie-International Edition. 2013 ;52:13601-13605.
Zhang W, Liu N, Schienebeck CM, Decloux K, Zheng SQ, Werness JB, Tang WP. Catalytic Enantioselective Halolactonization of Enynes and Alkenes. Chemistry-A European Journal. 2012 ;18:7296-7305.
Huang SY, Li XX, Lin CL, Guzei IA, Tang WP. Rhodium-catalyzed 1,3-acyloxy migration and subsequent intramolecular 4+2 cycloaddition of vinylallene and unactivated alkyne. Chemical Communications. 2012 ;48:2204-2206.
Shu XZ, Shu DX, Schienebeck CM, Tang WP. Rhodium-catalyzed acyloxy migration of propargylic esters in cycloadditions, inspiration from the recent "gold rush". Chemical Society Reviews. 2012 ;41:7698-7711.
Li XX, Huang SY, Schienebeck CM, Shu DX, Tang WP. Rhodium-Catalyzed Carbonylation of 3-Acyloxy-1,4-enynes for the Synthesis of Cyclopentenones. Organic Letters. 2012 ;14:1584-1587.
Shu DX, Li XX, Zhang M, Robichaux PJ, Guzei IA, Tang WP. Rhodium-Catalyzed Carbonylation of Cyclopropyl Substituted Propargyl Esters: A Tandem 1,3-Acyloxy Migration 5+1 Cycloaddition. Journal of Organic Chemistry. 2012 ;77:6463-6472.
Shu XZ, Li XX, Shu DX, Huang SY, Schienebeck CM, Zhou X, Robichaux PJ, Tang WP. Rhodium-Catalyzed Intra- and Intermolecular 5+2 Cycloaddition of 3-Acyloxy-1,4-enyne and Alkyne with Concomitant 1,2-Acyloxy Migration. Journal of the American Chemical Society. 2012 ;134:5211-5221.
Liu RH, Zhang M, Wyche TP, Winston-McPherson GN, Bugni TS, Tang WP. Stereoselective Preparation of Cyclobutanes with Four Different Substituents: Total Synthesis and Structural Revision of Pipercyclobutanamide A and Piperchabamide G. Angewandte Chemie-International Edition. 2012 ;51:7503-7506.
Zhang M, Tang WP. Synthesis of Functionalized Cyclohexenone Core of Welwitindolinones via Rhodium-Catalyzed 5+1 Cycloaddition. Organic Letters. 2012 ;14:3756-3759.
Tang WP, Luo TP, Greenberg EF, Bradner JE, Schreiber SL. Discovery of histone deacetylase 8 selective inhibitors. Bioorganic & Medicinal Chemistry Letters. 2011 ;21:2601-2605.
Liu N, Schienebeck CM, Collier MD, Tang WP. Effect of halogenation reagents on halocyclization and Overman rearrangement of allylic trichloroacetimidates. Tetrahedron Letters. 2011 ;52:6217-6219.
Shu XZ, Huang SY, Shu DX, Guzei IA, Tang WP. Interception of a Rautenstrauch Intermediate by Alkynes for 5+2 Cycloaddition: Rhodium-Catalyzed Cycloisomerization of 3-Acyloxy-4-ene-1,9-diynes to Bicyclo 5.3.0 decatrienes. Angewandte Chemie-International Edition. 2011 ;50:8153-8156.
Liu N, Werness JB, Guzei IA, Tang WP. Intramolecular 1,4-addition of nitrogen nucleophile and bromine electrophile to conjugated 1,3-enyne. Tetrahedron. 2011 ;67:4385-4390.
Li XX, Zhang M, Shu DX, Robichaux PJ, Huang SY, Tang WP. Rhodium-Catalyzed Ring Expansion of Cyclopropanes to Seven-membered Rings by 1,5 C-C Bond Migration. Angewandte Chemie-International Edition. 2011 ;50:10421-10424.
Werness JB, Tang WP. Stereoselective Total Synthesis of (-)-Kumausallene. Organic Letters. 2011 ;13:3664-3666.
Werness JB, Tang WP. Synthesis of bromoallenyl pyrrolidines via 1,4-addition to 1,3-enynes. Science China-Chemistry. 2011 ;54:56-60.
Shu DX, Li XX, Zhang M, Robichaux PJ, Tang WP. Synthesis of Highly Functionalized Cyclohexenone Rings: Rhodium-Catalyzed 1,3-Acyloxy Migration and Subsequent 5+1 Cycloaddition. Angewandte Chemie-International Edition. 2011 ;50:1346-1349.