UW-Madison Chemistry Department Newsletter for 5/29/2012

Bucky UNIVERSITY OF WISCONSIN-MADISON
DEPARTMENT OF CHEMISTRY NEWSLETTER
XXXVI - No. 19 May 29th, 2012

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After 42 years, Legendary Chemistry Instructor Dr. Ieva Reich to Retire
Chemistry Instructor Ieva Reich is honored for her 42 year career at UW-Madison. Reich has mentored thousands of students who say they respect and admire her innovative teaching and passion for complex and difficult material.  Check out the article at http://news.ls.wisc.edu/?p=9337.
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Rosana Pérez-Ellmann, Academic Department Manager, Department of Chemistry, College of Letters and Science is One of Five Named Winners of Classified Employee Recognition Awards
Rosana Pérez-Ellmann joined the chemistry department about three years ago following a stint in a senior management position at Lands End.
“In that short period of time she has transformed our business office and, indeed, our entire methodology in terms of personnel evaluation throughout the department," James Weisshaar, department chair, said in the award nomination. "She has the entire operation running very smoothly and she is developing a  farm team' of excellent workers who can move into higher positions as they open up. She raises the level of everyone's game   faculty and staff alike," Weisshaar added. "Absolutely outstanding," "fantastic," and "exceptional" are words that have been used to describe Pérez-Ellmann's job performance. She thinks deeply about how to enhance the department's performance in all areas involving faculty, students and staff. "She leads by example and by her outcome-based management ideas. She makes everyone around her a better worker by demonstrating her commitment to excellence every day, in every situation," said Weisshaar.
She is credited with leading the way toward creation of the department's new board of directors   a group of highly successful business people from companies most interested in the department's graduates. She has made creative contributions to the department's outreach and fundraising efforts.
Professor Robert Hamers said Pérez-Ellmann is an out-of-the-box thinker who has transformed the department by substantially increasing efficiency, productivity and the level of service provided, while improving the overall climate throughout the department.
She serves on the Campus Climate and Diversity Committee and on a review committee for hiring department administrators across campus. She is also a volunteer on her department's Partners in Giving team. Off campus, she has been active in the Madison schools, working with them to develop technology grants, and she has organized an event to obtain winter hats and mittens for school children who need them. Congratulations Rosana!!
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Professor Josh Coon, UW-Madison Researcher Wins Klaus Biemann Medal
Josh Coon's work has weight. It's right there in the name: mass spectrometry. It's there in the results, too, enabling science by giving researchers an ever-sharper understanding of the molecules that make up living things. "It greatly broadens the scope of biological questions you can ask," Coon says. And it all comes down to mass. "The field is about making instruments designed to measure the mass of molecules," says Coon, professor of chemistry and biomolecular chemistry at the University of Wisconsin-Madison. "From that, you can figure out all kinds of things about them: their formation, the structure, the amount you have. You can get really creative once you have mass, and that all started with Klaus Biemann in the 1960s."
Coon served as a post-doctoral researcher in the University of Virginia lab of Donald Hunt, co-inventing electron transfer dissociation, a method of mass spectrometry. Hunt did his post-doctoral work in Biemann's lab at Massachusetts Institute of Technology. The American Society for Mass Spectrometry has tightened the academic family circle by awarding Coon its Klaus Biemann Medal for "significant achievement in basic or applied mass spectrometry made by an individual early in his or her career."
In a sense, mass spectrometers throw molecules at a wall - slicing them up with streams of electrons and bending their path with radiofrequency fields - and record the masses of the pieces. Just how far off their original path the component parts are bumped and pulled reveals how much the molecule weighed. Coon is best known for his contribution to electron transfer dissociation, which substitutes the electrons with a stream of anions, small molecules carrying extra electrons. "ETD allows you to characterize different types of proteins, and works well for types of proteins that mass spec isn't typically good with," says Coon, who continues to improve ETD in his UW-Madison lab. "We grind up a cell and look at what's in it. It's shotgun proteomics."
About 500 mass spectrometry machines around the world incorporate ETD to extend their capabilities. In 2011, there were 140 published scientific studies that made direct use of the technology. That may be the long way to measure the impact of Coon's research. Asking collaborator Alan Attie is the short route. "Without him, without what his work allows us to do?" asked Attie, a UW-Madison biochemist studying the connections between obesity and Type 2 diabetes, "I think I would be crying." Attie calls Coon a pioneer in "phosphoproteomics," the study of the way addition and subtraction of phosphorus atoms help or hinder complex proteins that drive so much of the necessary work inside living cells. "A lot of the signaling pathways in us do what they do because they stimulate a cascade of events in cells that attach or detach phosphorus from proteins," Attie says. "What Josh has done is develop techniques that survey the thousands of proteins in a cell to find which ones have phosphorus and which don't, and go even deeper to find which particular amino acid piece of the protein is the attachment point for phosphorus."
Attie's lab work has progressed down lines of inquiry they would not even have considered without Coon's enlightening mass spectrometry methods. "He was essential in finding a signaling pathway in mice that determines whether an obese mouse gets Type 2 diabetes or not," Attie says. "We can't even look there without Josh, much less find anything." Enabling more research like Attie's is the goal for Coon. "Now we are working on combining ETD with other new technologies and ideas to extend the medical impact of mass spectrometry by monitoring protein differences across hundreds or even thousands of people." Simply lining up 100 mass spectrometers won't do, he says. "There's a lot of variability in the things we see in each experiment," Coon says. "You need both the throughput to handle tissue samples from an enormous number of people and the repeatability to make sure you can compare all those results." It's the steps that led from Biemann's lab into Hunt's lab and Coon's lab - and into labs around the world studying how to tackle outstanding biomedical problems - that will be foremost in Coon's mind when he accepts the Biemann Medal at the ASMS annual conference later this month. "I want to talk a bit about my perspective on the people who do this work," Coon says. "There are a lot of people who make your group what it is, and they should all share in the success."
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SNOUT OUT SCHEDULED FOR SATURDAY, SEPTEMBER 8th, 2012 AT RENNEBOHM PARK
This year's Snout-Out has been scheduled for Saturday, September 8th in Rennebohm Park. This will be the 29th annual departmental picnic, and as always there will be plenty of food, refreshments, and the softball tournament for the coveted trophy. More information (and registration forms) to come at a later date.
See you then! The GSFLC.
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2012 Dates of Finance/Department Meetings
Department/Executive Committee Meetings - Tuesdays - 1:30 PM - Room 9341 Chemistry

TBA

Finance Committee Meetings - Tuesdays - 1:30 PM - Room 1130

TBA

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SEMINARS
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Thursday, September 6th, 2012 - Organic Seminar, 11:00 a.m., Room 1315 Chemistry Building. Professor Michael M. Haley, University of Oregon.
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Monday, September 12th, 2012 - Inorganic Chemistry Seminar, 3:30 p.m., Room 1315 Chemistry Building. Nuru Stracey, UW-Madison.
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Wednesday, September 12th, 2012 - Inorganic Chemistry Seminar, All Day, Room 1315 Chemistry Building. Professor Travis Williams, University of Southern California.
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SCIENCE IS FUN - SUMMER EXTRAVAGANZA

Summer Extravaganza

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RECENT PUBLICATIONS
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INORGANIC CHEMISTRY Two-armed silicon.
West, R*.
NATURE, 485 (7396):49-50; MAY 3 2012.
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Formation of Self-Assembled Monolayers of pi-Conjugated Molecules on TiO2 Surfaces by Thermal Grafting of Aryl and Benzyl Halides.
English, CR; Bishop, LM; Chen, JX; Hamers, RJ*.
LANGMUIR, 28 (17):6866-6876; 10.1021/la300271h MAY 1 2012.
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Forging Isopeptide Bonds Using Thiol-Ene Chemistry: Site-Specific Coupling of Ubiquitin Molecules for Studying the Activity of Isopeptidases.
Valkevich, EM; Guenette, RG; Sanchez, NA; Chen, YC; Ge, Y; Strieter, ER*.
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 134 (16):6916-6919; 10.1021/ja300500a APR 25 2012.
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Infrared Spectra at a Conical Intersection: Vibrations of Methoxy.
Nagesh, J; Sibert, EL*.
JOURNAL OF PHYSICAL CHEMISTRY A, 116 (15):3846-3855; 10.1021/jp2116627 APR 19 2012.
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Photoisomerization and Relaxation Dynamics of a Structurally Modified Biomimetic Photoswitch.
Dunkelberger, AD; Kieda, RD; Shin, JY; Paccani, RR; Fusi, S; Olivucci, M; Crim, FF*.
JOURNAL OF PHYSICAL CHEMISTRY A, 116 (14):3527-3533; 10.1021/jp300153a APR 12 2012.
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Trimethylsilyl-Substituted Hydroxycyclopentadienyl Ruthenium Hydrides as Benchmarks To Probe Ligand and Metal Effects on the Reactivity of Shvo Type Complexes.
Casey, CP*; Guan, HR.
ORGANOMETALLICS, 31 (7):2631-2638; 10.1021/om20074531 APR 9 2012.
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High-Yield Synthesis of PPh3-Ligated Decanuclear Tl-Pd Cluster, Pd-9[Tl(acac)](CO)(9)(PPh3)(6): Comparative Analysis of Tl(I)-Pd(0) Bonding Connectivities with Known Tl-Pd Clusters and Resulting Insight Concerning Their Dissimilar Dynamic Solution Behavior.
Mednikov, EG; Vo, N; Fry, CG*; Dahl, LF*.
ORGANOMETALLICS, 31 (7):2878-2886; 10.1021/om201150x APR 9 2012.
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Copper(II)-mediated oxidative cyclization of enamides to oxazoles.
Wendlandt, AE; Stahl, SS*.
ORGANIC & BIOMOLECULAR CHEMISTRY, 10 (19):3866-3870; 10.1039/c2ob25310k 2012.
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Enhancement of alpha-Helix Mimicry by an alpha/beta-Peptide Foldamer via Incorporation of a Dense Ionic Side-Chain Array.
Johnson, LM; Mortenson, DE; Yun, HG; Horne, WS; Ketas, TJ; Lu, M; Moore, JP; Gellman, SH*.
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 134 (17):7317-7320; 10.1021/ja302428d MAY 2 2012.
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Genome sequencing of ovine isolates of Mycobacterium avium subspecies paratuberculosis offers insights into host association.
Bannantine, JP; Wu, CW; Hsu, CY; Zhou, SG; Schwartz, DC*; Bayles, DO; Paustian, ML; Alt, DP; Sreevatsan, S; Kapur, V; Talaat, AM.
BMC GENOMICS, 13 10.1186/1471-2164-13-89 MAR 12 2012.
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Ethylene Sensing by Silver(I) Salt-Impregnated Luminescent Films.
Cintron, MS; Green, O; Burstyn, JN*.
INORGANIC CHEMISTRY, 51 (5):2737-2746; 10.1021/ic102590f MAR 5 2012.
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Combined Spectroscopic/Computational Studies of Vitamin B-12 Precursors: Geometric and Electronic Structures of Cobinamides.
Reig, AJ; Conrad, KS; Brunold, TC*.
INORGANIC CHEMISTRY, 51 (5):2867-2879; 10.1021/ic202052g MAR 5 2012.
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Photolysis, OH reactivity and ozone reactivity of a proxy for isoprene-derived hydroperoxyenals (HPALDs).
Wolfe, GM; Crounse, JD; Parrish, JD; St Clair, JM; Beaver, MR; Paulot, F; Yoon, TP; Wennberg, PO; Keutsch, FN*.
PHYSICAL CHEMISTRY CHEMICAL PHYSICS, 14 (20):7276-7286; 10.1039/c2cp40388a 2012.
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Copyright © 2012 Thomson ISI
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EMPLOYMENT OPPORTUNITIES
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NONE FOR THIS NEWSLETTER
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FACULTY POSITIONS/TEMPORARY FACULTY/ACADEMIC POSITIONS
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The Chemistry Department at Grand Valley State University has two openings for Visiting Professors to teach lectures and labs in the areas of general chemistry and/or biochemistry. The positions are full-time for one academic year (mid-August 2012 through the end of April 2013). Visiting faculty positions may be extended for two additional one-year appointments, depending on departmental need and faculty performance.
QUALIFICATIONS: Candidates must have a graduate degree in Chemistry, Biochemistry or related discipline. A doctoral degree and/or undergraduate teaching experience is preferred. Demonstrated ability or experience in teaching lectures and labs is especially desirable. The Chemistry Department values candidates who demonstrate a commitment to excellence in undergraduate teaching and an ability to work in a collaborative environment with a diverse population of colleagues and students. Mentoring by our 30 experienced tenure-track faculty is available.
RESPONSIBILITIES: Responsibilities of visiting faculty include teaching lectures, discussions, and labs for introductory service courses in general and organic chemistry. Other teaching duties may be assigned, depending on departmental need and the candidate's qualifications. A typical teaching load is about 15 assigned teaching hours per semester.
SALARY: Salary is commensurate with experience and qualifications. Please see the Human Resources web page for complete information about benefits available for visiting faculty. Http://www.gvsu.edu/hro/.
HOW TO APPLY: Applications should be sent to Todd A Carlson (department chair) by e-mail
carlsont@gvsu.edu. Please attach following Word (.doc) or Adobe (.pdf) documents: An application cover letter; A Curriculum Vita; A statement of teaching philosophy. Applicants must also arrange for two letters of recommendation to be sent separately by e-mail to: carlsont@gvsu.edu or by mail to: Visitor Search Committee, Chemistry Department, 312 Padnos Hall, Grand Valley State University, Allendale, MI 49401.
APPLICATION DEADLINE: Review of applications will begin May 28, 2012 and will continue until the
positions are filled.
FOR MORE INFORMATION: See our department website at: http://www.gvsu.edu/chem/, Grand Valley State University, Allendale, Michigan 49401 (616) 331-5000, For more information about Grand Valley, see our website at: http://www.gvsu.edu.
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POSTDOCTORAL POSITIONS AND/OR JOBS
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NONE FOR THIS NEWSLETTER
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Please submit all newsletter information or address changes to: goldade@chem.wisc.edu or 262-0293. Thanks.
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DETAILS ARE AVAILABLE IN ROOM 1146.
NEXT NEWSLETTER IS ON JUNE 11th, 2012