Department of Chemistry Newsletter for 01/25/2016

Bucky UNIVERSITY OF WISCONSIN-MADISON
DEPARTMENT OF CHEMISTRY NEWSLETTER
XL - No. 02 January 25th, 2016

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KYOUNG-SHIN CHOI NAMED A VILAS ASSOCIATE
Congratulations to Professor Kyoung-Shin Choi on being named a Vilas Associate at UW-Madison. The Vilas Associates Competition recognizes new and on-going research of the highest quality and significance. Recipients are chosen competitively by the Divisional Research Committees of the Office of the Vice Chancellor for Research and Graduate Education on the basis of a detailed proposal. Congratulations, Kyoung-Shin!
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PROFESSOR YING GE RECEIVES 2016 GEORGES GUIOCHON FACULTY FELLOWSHIP
Congratulations to Professor Ying Ge on receiving the 2016 Georges Guiochon Faculty Fellowship, which is given to an individual advancing the field of liquid phase separations who is within 10 years of their first academic appointment. The award honors Professor Guiochon, a major figure in the field of HPLC for over 50 years. Congratulations, Ying!                          
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2016 Dates of Finance/Department Meetings
Department/Executive Committee Meetings - Tuesdays - 1:30 PM - Room 9341 Chemistry

2/09/2016 3/08/2016 4/12/2016 5/10/2016

Finance Committee Meetings - Tuesdays - 1:30 PM - Room 1130

2/02/2016 2/16/2016 3/01/2016 3/29/2016
4/05/2016 4/26/2016 5/03/2016 5/17/2016

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SEMINARS
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Wednesday, January 27th, 2016 - Inorganic Seminar, 3:30 pm, Room 1315 Chemistry Building. Angela Marquard, UW Madison (Goldsmith Group) "Inorganic Student Seminar"
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Thursday, January 28th, 2016 - General, Department, Chemical Biology, Organic Seminar, 11:00 am, 1315 Chemistry. Prof. Eric Strieter, UW-Madison Department of Chemistry "Special Department Seminar "Dissecting the functions of deubiquitinases using chemical tools""
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Thursday, January 28th, 2016 - Department, Analytical Seminar, 12:15 pm, 1315 Chemistry (Seminar Hall). Prof. Hongrui Jiang, UW-Madison ECE "Analytical Seminar"
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Saturday, January 30th, 2016 - General Outreach, 9:00 am, UW-Madison Engineering Hall. Dr. Matt Bowman, UW-Madison Department of Chemistry "Wisconsin Middle School Regional Science Bowl"
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Tuesday, February 2nd, 2016 - Department, Physical, Theoretical Seminar, 11:00 am, 1315 Chemistry Building - Seminar Hall. Professor Michael Heaven, Emory University "The unique bonding characteristics of beryllium and the Group IIA metals"
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Tuesday, February 2nd, 2016 - Organic Seminar, 3:30 pm, 1315 Chemistry (Seminar Hall). Professor Kevin Moeller, Washington University "Organic Seminar "From oxidative cyclizations to microelectrode arrays to the processing of lignin derived materials: Using electrochemistry to solve synthetic problems of structure and location""
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Wednesday, February 3rd, 2016 - Inorganic Seminar, 3:30 pm, Room 1315 Chemistry. Prof. Ang Wee Han, National University of Singapore "Inorganic Seminar"
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Thursday, February 4th, 2016 - Analytical, Chemical Biology Seminar, 12:15 pm, 1315 Chemistry. Prof. David Beebe, UW-Madison Engineering Dept. "Analytical Seminar - Title TBD"
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Monday, February 8th, 2016 - Materials, Physical Seminar, 3:30 pm, 1315 Chemistry. Prof. Carsten Sievers, Georgia Tech "Materials Seminar - Title TBD"
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Tuesday, February 9th, 2016 - Department, Physical, Theoretical Seminar, 11:00 am, 1315 Chemistry Building - Seminar Hall. Professor Sara Vaiana, Arizona State University "Physical Chemistry Seminar"
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Tuesday, February 9th, 2016 - Department Special Event, 1:30 pm, 9341 Chemistry Building. Department of Chemistry, "Department Meeting"
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Wednesday, February 10th, 2016 - Inorganic Seminar, 3:30 pm, Room 1315 Chemistry Building. Stephanie Dillon, UW Madison (Brunold Group) "Inorganic Student Seminar"
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Friday, February 12th, 2016 to Saturday, February 13th, 2016 - Department Special Event, 4:00 pm, "Graduate Recruiting Visit Weekend"
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Monday, February 15th, 2016 - Department, Physical, Theoretical Seminar, 2:00 pm, 1315 Chemistry Building - Seminar Hall. Professor Kurt Kremer, Max Planck Institute for Polymer Research "Ferry Lectures in Physical Chemistry"
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Tuesday, February 16th, 2016 - Department, Physical, Theoretical Seminar, 11:00 am, 1315 Chemistry Building - Seminar Hall. Professor Kurt Kremer, Max Planck Institute for Polymer Research "Ferry Lectures in Physical Chemistry"
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Wednesday, February 17th, 2016 - Inorganic Seminar, 3:30 pm, Room 1315 Chemistry Building. Nathan Neff-Mallon, UW-Madison (Wright and Brunold Group) "Inorganic Student Seminar"
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Thursday, February 18th, 2016 - Chemical Biology, Organic Seminar, 11:00 am, 1315 Chemistry - Seminar Hall. Dr. Clifton Barry, NIH, NIAID "Organic Seminar "Exploiting the biochemistry of trehalose to develop real-time imaging probes for tuberculosis""
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Thursday, February 18th, 2016 - Analytical, Materials Seminar, 12:15 pm, 1315 Chemistry (Seminar Hall). Margaret Robinson, UW Madison - Hamers group "Analytical Seminar - Title TBD"
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Monday, February 22nd, 2016 - Department, Physical, Theoretical Seminar, 3:00 pm, Room 8335 Chemistry Building. Professor Dominika Zgid, University of Michigan "Theoretical Chemistry Institute Seminar"
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Tuesday, February 23rd, 2016 - Department, Physical, Theoretical Seminar, 11:00 am, 1315 Chemistry Building - Seminar Hall. Professor Arthur Bragg, Johns Hopkins University "Physical Chemistry Seminar"
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Wednesday, February 24th, 2016 - Inorganic Seminar, 3:30 pm, Room 1315 Chemistry. Prof. Raj Gounder, University of Purdue "Inorganic Seminar"
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Friday, February 26th, 2016 to Saturday, February 27th, 2016 - Department Special Event, 4:00 pm, "Graduate Recruiting Visit Weekend"
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NSF'S RESEARCH EXPERIENCE FOR UNDERGRADUATES (REU)
May 31 - August 6, 2016
The summer undergraduate research program at the University of Southern California. Briefly, this ten-week program is an opportunity for students to conduct research in residence in our Chemistry Department. We offer projects in chemistry, biochemistry, and nanoscience. Student health insurance and travel costs are covered by the Chemistry Department, and students will also receive a stipend. Housing is not covered. Sophomores and juniors who are U.S. citizens or permanent residents may apply online by visiting: http://chem.usc.edu/undergraduate/reu_prog.html.
Please be advised that the application deadline is February 15, 2016. For more information, please don't hesitate to contact Program Coordinator, Anahit Martirosyan by email at amartiro@usc.edu. Department of Chemistry, Dornsife College of Letters, Arts, & Sciences, University of Southern California.
Program Support Includes $5000 Stipend, Housing, Student Health Insurance, and Travel. Broad selection of research groups in alternative energy, chemical physics, chemical biology, drug discovery, inorganic, materials/polymers, nanoscience, organic, physical, and theoretical. Open to sophomores or juniors who are US citizens or permanent residents. Women and underrepresented minorities are encouraged to apply. Fill out an application online by February 15, 2016. http://chem.usc.edu/reu.html.
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SCIENCE ILLUSTRATION AT THE MERI GALLERY
As a member of the McPherson Eye Research Institute, Rodney Schreiner would like to call your attention to the opening of an exhibition the MERI gallery on the 9th floor of the Wisconsin Institutes for Medical Research, 1111 Highland Avenue. The exhibition is titled SHARED VISION: TALES OF SCIENCE ILLUSTRATION, and features the work of science illustrators connected to UW-Madison, along with explanatory text that describes how scientific data has been transformed into engaging artwork that communicates scientific ideas.
Among the work on display are illustrations prepared by Adam Steinberg working with Prof. Ron Raines, and photographs by Ilia Guzei of Blaschka glass models of sea creatures created in the 19th century and now in the collection of the UW-Madison Zoology Museum.
Meet the artists at the exhibition opening reception on Wednesday, January 27th from 5pm to 7:00pm! Of particular interest is that two of the ten winning images were submitted by members of our own chemistry department: Audrey Forticaux and Matthew Faber, both students of Prof. Jin.
If you happen to be at the west end of campus with a few free minutes, do stop in to see the show. The images are captivating, and the views of campus from the 9th floor of the WIMR building are spectacular, too.
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RECENT PUBLICATIONS
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Synthesis, structure and chemistry of dinuclear and trinuclear hexamethylbenzene ruthenium acyl thiolate compounds.
Ramirez-Andrade, M; de la Cruz-Cruz, JI; Leyva-Ramirez, MA; Guzei, IA*; Paz-Sandoval, MA.
Journal of Organometallic Chemistry, 801 171-182; 10.1016/j.jorganchem.2015.11.001 JAN 1 2016.
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Expanding the family of heterobimetallic Bi-Rh paddlewheel carboxylate complexes via equatorial carboxylate exchange.
Sunderland, TL; Berry, JF*.
DALTON TRANSACTIONS, 45 (1):50-55; 10.1039/c5dt03740a 2016.
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Metallic CoS2 nanowire electrodes for high cycling performance supercapacitors.
Ren, R; Faber, MS; Dziedzic, R; Wen, ZH; Jin, S*; Mao, S; Chen, JH.
NANOTECHNOLOGY, 26 (49):10.1088/0957-4484/26/49/494001 DEC 11 2015.
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Covalent Immobilization of Caged Liquid Crystal Microdroplets on Surfaces.
Guo, XR; Manna, U; Abbott, NL*; Lynn, DM*.
Acs Applied Materials & Interfaces, 7 (48):26892-26903; 10.1021/acsami.5b09595 DEC 9 2015.
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Operando Analysis of NiFe and Fe Oxyhydroxide Electrocatalysts for Water Oxidation: Detection of Fe4+ by Mossbauer Spectroscopy.
Chen, JYC; Dang, LN; Liang, HF; Bi, WL; Gerken, JB; Jin, S*; Alp, EE; Stahl, SS*.
Journal of the American Chemical Society, 137 (48):15090-15093; 10.1021/jacs.5b10699 DEC 9 2015.
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Carbohydrate-Aromatic Interactions in Proteins.
Hudson, KL; Bartlett, GJ; Diehl, RC; Agirre, J; Gallagher, T; Kiessling, LL*; Woofson, DN.
Journal of the American Chemical Society, 137 (48):15152-15160; 10.1021/jacs.5b08424 DEC 9 2015.
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Thermal Isomerizations of Diethynyl Cyclobutadienes and Implications for Fullerene Formation.
Esselman, BJ; Emmert, FL; Wiederhold, AJ; Thompson, SJ; Slipchenko, LV; McMahon, RJ*.
JOURNAL OF ORGANIC CHEMISTRY, 80 (23):11863-11868; 10.1021/acs.joc.5b01864 DEC 4 2015.
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Electrochemical Synthesis of Photoelectrodes and Catalysts for Use in Solar Water Splitting.
Kang, D; Kim, TW; Kubota, SR; Cardiel, AC; Cha, HG; Choi, KS*.
CHEMICAL REVIEWS, AMER CHEMICAL SOC, SN 0009-2665, 1520-6890, DEC 9, 2015, VL 115.
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Transition State Gauche Effects Control the Torquoselectivities of the Electrocyclizations of Chiral 1-Azatrienes.
Patel, A; Vella, JR; Ma, ZX; Hsung, RP*; Houk, KN.
JOURNAL OF ORGANIC CHEMISTRY, AMER CHEMICAL SOC. SN 0022-3263, DEC 4, 2015, VL 80, IS 23.
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A dual cryogenic ion trap spectrometer for the formation and characterization of solvated ionic clusters.
Marsh, BM; Voss, JM; Garand, E*.
Journal of Chemical Physics, Amer Inst Physics, SN 0021-9606, 1089-7690, NOV 28, 2015, VL 143 IS 20.
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Characterization of structural elements in native autoinducing peptides and non-native analogues that permit the differential modulation of AgrC-type quorum sensing receptors in Staphylococcus aureus.
Tal-Gan, Y; Ivancic, M; Cornilescu, G; Blackwell, HE*.
ORGANIC & BIOMOLECULAR CHEMISTRY, 14 (1):113-121; 10.1039/c5ob01735a 2016.
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Kinetic and thermodynamic characterization of C-N bond rotation by N-methylacetohydroxamic acid in aqueous media.
Sippl, SP; White, PB; Fry, CG*; Volk, SE; Ye, LX; Schenck, HL.
MAGNETIC RESONANCE IN CHEMISTRY, 54 (1):46-50; 10.1002/mrc.4318 JAN 2016.
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Target selection by natural and redesigned PUF proteins.
Porter, DF; Koh, YY; VanVeller, B; Raines, RT*; Wickens, M.
Proceedings of the National Academy of Sciences of the United States of America, 112 (52):15868-15873; 10.1073/pnas.1508501112 DEC 29 2015.
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Molecular Electronic Effects on the Thermal Grafting of Aryl Iodides to TiO2 Surfaces.
English, CR; Hamers, RJ*.
Journal of Physical Chemistry C, 119 (50):27972-27981; 10.1021/acs.jpcc.5b08333 DEC 17 2015.
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DCI Transport through Dodecyl Sulfate Films on Salty Glycerol: Effects of Seawater Ions on Gas Entry.
Shaloski, MA; Sobyra, TB; Nathanson, GM*.
Journal of Physical Chemistry A, 119 (50):12357-12366; SI 10.1021/acs.jpca.5b07298 DEC 17 2015.
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Divergent Reactivity of Rhodium(I) Carbenes Derived from Indole Annulations.
Li, XX; Li, H; Song, WZ; Tseng, PS; Liu, LY; Guzei, IA*; Tang, WP*.
Angewandte Chemie-international Edition, 54 (44):12905-12908; 10.1002/anie.201505329 OCT 26 2015.
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18-Electron Rule and the 3c/4e Hyperbonding Saturation Limit.
Landis, CR*; Weinhold, F*.
JOURNAL OF COMPUTATIONAL CHEMISTRY, 37 (2):237-241; SI 10.1002/jcc.24001 JAN 15 2016.
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Measurement of Ultrafast Excitonic Dynamics of Few-Layer MoS2 Using State-Selective Coherent Multidimensional Spectroscopy.
Czech, KJ; Thompson, BJ; Kain, S; Ding, Q; Shearer, MJ; Hamers, RJ*; Jin, S*; Wright, JC*.
ACS NANO, 9 (12):12146-12157; 10.1021/acsnano.5b05198 DEC 2015.
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COPYRIGHT © 2016 THOMSON ISI
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EMPLOYMENT OPPORTUNITIES
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NONE FOR THIS NEWSLETTER
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FACULTY POSITIONS/TEMPORARY FACULTY/ACADEMIC POSITIONS
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Visiting Assistant Professor of Chemistry at Washington and Lee University. The Department of Chemistry and Biochemistry at Washington and Lee University seeks to fill a full-time Visiting Position to teach Organic Chemistry and the associated lab.  The position is for one year and is renewable for a second year upon satisfactory performance.  The position starts in August 2016 and requires a Ph.D. in Chemistry and relevant teaching experience.  Summer research opportunities are available.  Review of applications will begin immediately and continue until the position is filled. W&L is a highly selective, independent, co-educational, liberal arts college of 1800 students located in Lexington, VA, three hours southwest of Washington, DC. W&L is an equal opportunity employer. Applicants should send a CV, a letter of application, a one page statement of teaching philosophy, unofficial graduate and undergraduate transcripts, and three letters of reference to: Lisa Alty, Chemistry@wlu.edu.
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Pacific University, Assistant Professor, Analytical Chemistry, Forest Grove, OR. We invite applications for a tenure-track Assistant Professor of Chemistry specializing in Analytical Chemistry to begin August 2016. Applicants must have a Ph.D. in chemistry and demonstrated commitment to excellence in teaching as well as scholarship involving undergraduates. Post-doctoral experience and college or university teaching experience are desired.
Teaching Expectations: Teaching responsibilities will include general chemistry, a quantitative analysis course with lab, and an instrumental analysis course with lab. Additional teaching responsibilities may include departmental service courses such as chemistry seminar, chemical literacy, or courses for non-majors. A full time teaching load is 20 teaching credits. Lecture courses meeting three times a week for 65 minutes receive four teaching credits, and each three-hour laboratory section receives two teaching credits. Faculty also mentor senior capstone projects.
Research Opportunities: The College of Arts and Sciences supports the chemistry department's efforts to engage our students in meaningful research experiences. All chemistry majors are required to complete a senior capstone consisting of either a one-semester project or two-semester research-based thesis. In this context mentoring experiences are encouraged. We therefore seek a collegial scholar-teacher whose research interests complement existing expertise in the department. We expect the successful candidate to establish an active research program with undergraduates. The research program must be successful and feasible in our liberal arts college setting; it should also be attractive to our student body, which includes some who go on to pursue graduate work, many preparing for professional school in the health professions (e.g., optometry, physical therapy, pharmacy), as well as some pursuing teaching, environmental chemistry, and other professional work within, for instance, high tech industries. The chemistry department has a range of major instrumentation. Start-up funds are provided.
Service Expectations: The successful candidate is expected to participate in service tasks at the departmental, college and university levels.
Application Requirements: To apply, please submit a cover letter, CV, statement of teaching philosophy, a research statement that includes a research plan appropriate for a liberal arts institution, unofficial undergraduate and graduate transcripts, and arrange for three letters of recommendation to be sent directly. Please combine all application materials (except unofficial transcripts and letters of reference) into a single file (.pdf or .doc), in the order listed above, with the following naming: Last name, First name, AChem 2015. Send application materials electronically to Patty Larkins (address below); put Analytical Chemistry 2015 as the subject in your e-mail. Patty Larkins, plarkins@pacificu.edu, Administrative Assistant, School of Natural Sciences, Pacific University, 2043 College Way, Forest Grove, OR 97116. Questions should be addressed to Paige Hall, Assistant Professor of Chemistry, at paige.hall@pacificu.edu. Pacific University is an affirmative action/equal opportunity employer. Applicants must be U.S. worker (includes U.S. citizens, permanent residents, foreign nationals granted temporary residence under one of the 1986 legalization programs, refugees, and asylees). Review of applications will begin Dec 1 and continue until the position is filled.
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Faculty Position in Chemistry at Michigan State University. Lyman Briggs College (LBC) at Michigan State University (MSU) invites applications for an academic year chemistry faculty position in the Academic Specialist Appointment System to join the college's chemistry group in August of 2016. The successful candidate will teach introductory undergraduate chemistry lectures and teach and supervise associated general chemistry laboratories.
Candidates must be committed to undergraduate teaching and should have a master's degree or Ph.D. in chemistry or chemical education in hand by August 15, 2016. The position requires expertise and/or teaching experience in general chemistry lecture and laboratory experiences. The successful candidate will be committed to advancing excellence in the teaching of introductory courses in general chemistry and will join the college's ongoing efforts to reform undergraduate STEM education. Experience with instructional strategies that engage students in active learning is especially desirable. The ideal candidate should have disciplinary or pedagogical research interests in Chemistry or Chemical Education. A flexible and scholarly approach to teaching students and mentoring student employees is essential. The ideal candidate will be able to work with and encourage a diverse student body. The position offers exciting opportunities for individuals interested in teaching in a liberal-arts college with all of the resources of large "Big 10" research university.
Academic Specialists in LBC teach five courses each academic year. The chemistry group offers lecture and laboratory courses in general chemistry, including a joint biology-chemistry course for students entering with less mathematics preparation, and senior seminars. Academic specialists contribute professional service to the college, including membership on LBC committees. A candidate would also have the opportunity to work on teaching and learning projects as needs and interests arise. The chemistry academic specialist will start with a three-year probationary appointment that has the potential, after successful reappointment, to become a long-term position (for details see the MSU Faculty Handbook http://www.hr.msu.edu/documents/facacadhandbooks/academicspecialist/ASH_...). Reappointment and continuing appointment decisions are based on performance reviews that include peer and student teaching evaluations.
This position is listed on the MSU Applicant Page, Posting # 2596. Applications must be uploaded to MSU's online job application site (https://jobs.msu.edu). A complete application will include a c.v., a teaching portfolio, and a cover letter that outlines the candidate's expertise as it pertains teaching in the college as well as the pedagogical approaches the candidate employs. For details on teaching portfolios see: www.lymanbriggs.msu.edu/faculty/openPositions.cfm. In addition, three letters of recommendation addressing the candidate's teaching experience and expertise must be sent electronically by the recommenders through the application system.
Deadline to ensure consideration of applications is February 8th, 2016, but review of applications will continue until the position is filled. Questions regarding this position should be directed to: Dr. Ryan Sweeder, sweeder@msu.edu, Chair of the Chemistry Academic Specialist Search, Lyman Briggs College, 35 East Holmes Hall, Michigan State University, East Lansing, MI 48825-1107.
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Chemistry: Biochemistry and Organic Chemistry (2 Positions). Gustavus Adolphus College invites applications for two full-time one-year positions of Visiting Assistant Professor in the Department of Chemistry to begin September 1, 2016.
Minimum Required Qualifications: We seek candidates who have an earned doctorate, but will consider candidates who have achieved ABD status. Candidates must have demonstrated excellence in teaching. A commitment to undergraduate teaching is essential; in their application candidates should discuss their commitment to teaching a student-centered undergraduate chemistry curriculum in a liberal arts environment. Preferred Qualifications: We are interested in applicants who will complement our commitment to students and faculty from diverse cultural groups, and who will diversify the expertise and experiences represented in the department.
Major/Essential Functions: Biochemistry Position: The teaching load will be seven course equivalents. Primary teaching responsibilities will include biochemistry lecture and labs (200-level) and contributions to general education, including teaching during our interim January term (a one-month short course) as determined by the candidate and appropriate to the candidate's expertise and interests. The department anticipates a continued vacancy in this area, and the successful candidate may be considered for continuation into the 2017-18 academic year, contingent upon favorable review and the continuing needs of the College. Biochemistry at Gustavus is an interdisciplinary program with direct ties to both the Departments of Biology and Chemistry. Organic Position: The teaching load will be seven course equivalents. Primary teaching responsibilities will include Organic II lecture and labs (200-level), Organic I lecture and labs (100-level), and contributions to general education, including teaching during our interim January term (a one-month short course) as determined by the candidate and appropriate to the candidate's expertise and interests. Application and Institution Information: Electronic application is required; email application materials as separate PDFs to: chem-search@gustavus.edu. (NOTE: Please indicate in the email subject line which position you are applying for.) The application materials must include a letter of application, curriculum vitae, statements of teaching philosophy and research interests, undergraduate and graduate transcripts (scanned copies acceptable), and three confidential letters of professional recommendation (sent directly from the reference or letter service). The cover letter and letters of recommendation should be addressed to: Department of Chemistry, Gustavus Adolphus College, 800 W College Ave, Saint Peter, MN 56082-1498. Application information is also available at: www.gustavus.edu/jobs. For more details, visit the College's website at www.gustavus.edu/provost/newfaculty/ or email chem-search@gustavus.edu. Review of applications will begin on February 22, 2016, and continue until the position is filled.
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POSTDOCTORAL POSITIONS AND/OR JOBS
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Postdoctoral Scholar - Hackel Lab - University of Minnesota - Twin Cities. Two postdoctoral positions are immediately available in the Hackel lab at the University of Minnesota. Positions: Two postdoctoral positions are available for a funded project on protein engineering of novel targeting ligands using an innovative combinatorial library approach. We seek motivated researchers with a Ph.D. in any related discipline as we value the diverse perspectives and expertise of an interdisciplinary environment. Experience in molecular biology and protein chemistry are beneficial. A demonstrated record of scientific achievement, including publications and presentations, is essential. A successful candidate will demonstrate strong work ethic, creativity, and productivity.
Please send a brief description of your career goals, your curriculum vitae, and contact information for three references to: hackel@umn.edu.. For more information, please visit http://research.cems.umn.edu/hackel. The University of Minnesota is an equal opportunity educator and employer.
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Tetraphase Pharmaceuticals Inc. Tetraphase Pharmaceuticals is a clinical stage biopharmaceutical company utilizing its breakthrough synthetic chemistry technology platform to discover and develop next-generation tetracycline antibiotics. Our drug candidates address urgent unmet medical need for serious hospital- and community-acquired infections. We developed an emerging pipeline of potent novel antibiotics with the potential to treat a wide range of infections, including broad-spectrum and selective-spectrum infections. The company's lead product candidate, eravacycline, a broad spectrum intravenous (IV) with transition to oral antibiotic has completed enrollment in two phase 3 studies for the treatment of complicated intra-abdominal infections and complicated urinary tract infections. In addition, the Company is advancing TP-271 into phase 1 IV and oral single-ascending dose studies with a goal of targeting the treatment of respiratory tract infections including infections caused by bio threat organisms, in collaboration with NIAID. A third candidate, TP-6076, is currently completing IND-enabling studies, and demonstrates significantly improved Gram-negative activity, especially against Acinetobacter. Further, our discovery group currently evaluates a variety of future opportunities in the antibacterial, inflammation and oncology therapeutic segments. Working at Tetraphase offers a great opportunity to apply synthetic organic chemistry skills to drug discovery. We provide an ideal setting to learn about the many disciplines involved in drug discovery and development. For more information, visit our website at www.tphase.com Job Description: The Discovery Chemistry Post-Doctoral Scientist reports to a Senior Scientist, Discovery Chemistry. S/he acts as a champion for assigned program. S/he participates in the design and is responsible for the execution of medicinal chemistry and scale-up campaigns towards the discovery of novel antibiotics and other small molecule therapeutic agents. The duration of this post-doctoral position is one year, and can be extended to a maximum of two years. We are seeking candidates to start in the first quarter of 2016.
Specific responsibilities of the Discovery Chemistry Post-Doctoral Scientist include:
     •    Primary responsibility for this position is to support programs from the bench, relying on hands-on
          expertise to solve complex synthetic chemistry issues.
     •    Contributes to medicinal chemistry programs in antibacterial and other small molecule drug
          discovery.
     •    Scales-up material as needed to support in vivo testing and/or preclinical development activities.
     •    Gradually develops knowledge in integrating complex and diverse datasets towards rational SAR
          hypotheses.
     •    Creates intellectual property and assists in filing patent applications to generate strong IP estate for
          Tetraphase.
     •    Keeps up-to-date with scientific literature, especially emerging synthetic methodologies.
     •    Publishes scientific findings in peer-reviewed journals and other forums (conference presentations
          and posters).
     •    Maintains a proper laboratory notebook and a safe, clean laboratory and office area.
Qualifications:
     •    Ph.D. in organic chemistry, preferably on the synthesis of complex natural products.
     •    Emerging track record of scientific achievement in the field of synthetic chemistry and drug
          discovery evidenced by publications, patents, and external presentations.
     •    Strong communication skills and ability to effectively interact with colleagues and CROs.
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Please submit all newsletter information or address changes to: goldade@chem.wisc.edu or 262-0293. Thanks.
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DETAILS ARE AVAILABLE IN ROOM 1146.
NEXT NEWSLETTER IS ON FEBRUARY 1st, 2016