Chemistry Newsletter - 12/20/2004

 

University of Wisconsin-Madison

Department of Chemistry Newsletter


XXVIII - No. 42 December 20th, 2004

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Newsletter on Christmas Vacation

The Chemistry Newsletter is on Christmas Vacation next week. It will return next year. Continue to submit your newsletter items to me at: goldade@chem.wisc.edu. Thanks and have a Merry Christmas!!

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Professor Lingjun Li Wins NSF Career Award

The Chemistry Department has just heard that Professor Lingjun Li has won an NSF CAREER award, entitled: “Development of Integrated MS Strategies for Probing Peptidergic Signaling”. Please join us in congratulating Lingjun! Her achievements add to the stature of our fine department, and we are lucky to have her with us.

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Department and Finance Committee Meeting Schedule

Department/Executive Committee Meetings - Tuesdays - 1:30 PM - Room 9341 Chemistry

2/8/05

3/8/05

4/12/05

5/10/05

Finance Committee Meetings - Tuesdays - 1:30 PM - Room 1130

1/25/05

2/15/05

3/1/05

3/15/05

4/5/05

4/19/05

5/3/05

5/17/05

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SEMINARS

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Thursday, January 20th, 2005 - Analytical Seminar, 12:15 p.m., Room 1315 Chemistry Building. Stephanie Dekeyser, Li Group.

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Tuesday, January 25th, 2005 - Physical Seminar, 11:00 a.m., Room 1315 Chemistry Building. Tobin Sosnick, University of Chicago.

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Tuesday, January 25th, 2005 - Organic Seminar, 3:30 p.m., Room 1315 Chemistry Building. Professor Brian Stoltz, California Institute of Technology.

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Thursday, January 27th, 2005 - Organic Seminar, 11:00 a.m., Room 1315 Chemistry Building. Jonathan Grimm, Lee Group.

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Thursday, January 27th, 2005 - Analytical Seminar, 12:15 p.m., Room 1315 Chemistry Building. Neil Kelleher, University of Illinois. “Reading the Post-Translational Codes of Biology Using Tandem Mass Spectrometry of High Mass Ions”

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Analytical Seminar abstracts/announcements can be found at: http://analytical.chem.wisc.edu/analytical/writings/Seminars/spring2005.html.

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Physical Chemistry Student Seminar abstracts/announcements can be found at: http://www.chem.wisc.edu/physical/Home.html.

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Recent Publications

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Zhou, SG; Kile, A; Kvikstad, E; Bechner, M; Severin, J; Forrest, D; Runnheim, R; Churas, C; Anantharaman, TS; Myler, P; Vogt, C; Ivens, A; Stuart, K; Schwartz, DC.

Shotgun optical mapping of the entire Leishmania major Friedlin genome.

Molecular and Biochemical Parasitology, 138 (1): 97-106 Nov 2004.

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Popp, BV; Thorman, JL; Morales, CM; Landis, CR; Stahl, SS.

“Inverse-electron-demand” ligand substitution: Experimental and computational insights into olefin exchange at palladium(0).

Journal of the American Chemical Society, 126 (45): 14832-14842 Nov 17 2004.

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Konopka, MC; Weisshaar, JC.

Heterogeneous motion of secretory vesicles in the actin cortex of live cells: 3D tracking to 5-nm accuracy.

Journal of Physical Chemistry A, 108 (45): 9814-9826 Nov 11 2004.

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Liu, XD; Thirupathi, N; Guzei, IA; Verkade, JG.

An investigation of staudinger reactions involving cis-1,3,5-triazidocyclohexane and tri(alkylamino)phosphines.

Inorganic Chemistry, 43 (23): 7431-7440 Nov 15 2004.

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Clark, RW; Youn, H; Parks, RB; Cherney, MM; Roberts, GP; Burstyn, JN.

Investigation of the role of the N-terminal proline, the distal heme ligand in the CO sensor CooA.

Biochemistry, 43 (44): 14149-14160 Nov 9 2004.

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Pazicni, S; Lukat-Rodgers, GS; Oliveriusova, J; Rees, KA; Parks, RB; Clark, RW; Rodgers, KR; Kraus, JP; Burstyn, JN.

The redox behavior of the heme in cystathionine beta-synthase is sensitive to pH.

Biochemistry, 43 (46): 14684-14695 Nov 23 2004.

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Felitsky, DJ; Cannon, JG; Capp, MW; Hong, J; Van Wynsberghe, AW; Anderson, CF; Record, MT.

The exclusion of glycine betaine from anionic biopolymer surface: Why glycine betaine is an effective osmoprotectant but also a compatible solute.

Biochemistry, 43 (46): 14732-14743 Nov 23 2004.

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Hong, J; Capp, MW; Anderson, CF; Saecker, RM; Felitsky, DJ; Anderson, MW; Record, MT.

Preferential interactions of glycine betaine and of urea with DNA: Implications for DNA hydration and for effects of these solutes on DNA stability.

Biochemistry, 43 (46): 14744-14758 Nov 23 2004.

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Yi, CS; Yun, SY; Guzei, IA.

Intermolecular coupling reaction of cyclic amines and alkenes catalyzed by a ruthenium-hydride complex (PCy3)(2)(CO)RuHCl.

Organometallics, 23 (23): 5392-5395 Nov 8 2004.

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Kim, YJ; Lee, D.

Use of N-N bond stereodynamics in ring-closing metathesis to form medium-sized rings and macrocycles.

Organic Letters, 6 (23): 4351-4353 Nov 11 2004.

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Dhiman, A; Zhang, ZR; West, R; Becker, JY.

Electrochemical oxidation germacyclopentadienes (germoles).

Journal of Electroanalytical Chemistry, 573 (1): 139-146 Nov 15 2004.

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Zhou, S; Kile, A; Bechner, M; Place, M; Kvikstad, E; Deng, W; Wei, J; Severin, J; Runnheim, R; Churas, C; Forrest, D; Dimalanta, ET; Lamers, C; Burland, V; Blattner, FR; Schwartz, DC.

Single-molecule approach to bacterial genomic comparisons via optical mapping.

Journal of Bacteriology, 186 (22): 7773-7782 Nov 2004.

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Yu, XH; Bi, SW; Guzei, IA; Lin, ZY; Xue, ZL.

Zirconium, hafnium, and tantalum amide silyl complexes: Their preparation and conversion to metallaheterocyclic complexes via gamma-hydrogen abstraction by silyl ligands.

Inorganic Chemistry, 43 (22): 7111-7119 Nov 1 2004.

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Copyright © 2004 Thomson ISI

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2005 Summer Undergraduate Research Program at the University of Kansas in Lawrence

The program is designed for current junior or especially well-qualified sophomore science majors who are interested in a chemistry-related career. Students will be able to choose from research projects in all areas of chemistry and will work closely with senior faculty research advisors. Project titles, names of research directors and detailed descriptions of the specific projects are available on our website: http://www.chem.ku.edu/REU or by request. Each participant will receive a stipend of $3100 for 10 weeks of full-time research and will receive expense-paid room and board in university housing for a total compensation of ~$6000 with an additional allowance (up to $300) for travel. For the past eighteen years we have been funded by the NSF Research Experiences for Undergraduates (REU) program. Our program runs from May 25 to August 3 and the deadline for receipt of all application materials is February 1 to insure full consideration. We ask your help in calling this opportunity to the attention of your undergraduate chemistry students. We invite inquiries and applications from all qualified students and particularly ask your assistance in encouraging applications from women and minority students. Students who wish application forms, more information, or detailed project descriptions are invited to go to our website; write or contact: the Program Secretary, Jan Akers at (785) 864-5206, fax (785) 864-5156, email: jakers@ku.edu.

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EMPLOYMENT OPPORTUNITIES

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Medical College of Wisconsin. Research Technologist - Research. Gastroenterology. Work collaboratively on research projects using molecular, biochemical and cell biological techniques utilizing animal cell culture and zebrafish as the model systems. Study the role of an RNA-binding protein involved in gut development and perform experiments involving molecular, cellular and biochemical techniques. Techniques include Isolation and manipulation of DNA/RNA, immunocytochemistry, in situ hybridization, immunoprecipitation, SDS-PAGE, western blotting and RNAi methodologies. Maintain animal cell culture lines and assist in the maintenance/feeding of the zebrafish colony. Perform microinjection of DNA/RNA into newly fertilized zebrafish embryos. Assist in the preparation and maintainance of laboratory reagents/inventory. Maintain careful records/lab notebooks and participate in weekly lab meetings. Follow required quality assurance procedures and learn new laboratory techniques as needed. Bachelor's degree in Biology, Biochemistry or related field, and one year’s experience working in molecular biology including restriction enzyme digests, DNA/RNA isolation and plasmid purification. Prefer Master's degree or additional years experience applying relevant techniques. 40 hours per week in the MACC Fund Research Center Gastroenterology research laboratories. Scheduling flexibility will be required to accommodate some weekend hours. Competitive wage plus comprehensive benefits package including health, dental, disability and group term life insurance; retirement programs; paid vacation, sick and holiday time; and tuition reimbursement. Free parking in campus lot. Send resume and references to: Jane Martell, Medical College of Wisconsin, Department of Pediatrics, 8701 Watertown Plank Road, MFRC756 Milwaukee, WI 53226, Or Employment Applications Available from 8:30 a.m. to 5:00 p.m. weekdays at MCW Employment Office, 1st Floor, Medical Education Building, 8701 Watertown Plank Road, Milwaukee, WI 53226.

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The Procter & Gamble Company. We are looking for a PhD student within their last year of degree or a postdoctoral fellowship within a year of completing their research program. These time requirements reflect the fact that the we have an immediate opening and hope to be able to fill it no later than 2nd quarter of 2005. Qualified candidates must be US Citizens or permanent residents. Please share this message accordingly and encourage interested parties to apply to the position described below. Website Instructions: Applicants can use the URL immediately following and then activate the "Show/Hide Search Controls" link. Once at this level of the system, the applicant can enter "617" in the "Enter Key Word or Job Number (Optional)" link and be taken to the job description where the "Apply Online" feature is located. http://pg.sitebase.net/global/pages/content/global_rs_frame.html. (If this link does not work try http://www.pg.com/careers and click on "View Jobs and Apply Online"). R&D PhD Chemist/Life Scientist - Job No. 00000617. Procter & Gamble’s Fabric & Home Care Technology Division in Cincinnati, OH has an opening for a Ph.D. chemist or life scientist to work with external (suppliers and academic researchers) and internal R&D partners to develop novel enzyme/biochemical technologies for consumer product applications. The successful candidate must have a thorough mechanistic understanding of organic chemistry and biochemistry with a proven track record of accomplishment in bioorganic chemistry, assay development, and subsequent screening of product candidates. Familiarity with enzymes and relevant assays is also desirable. Previous experience in translating theoretical concepts to applied research projects is desired but not required. The candidate must also possess excellent communication skills and the ability to work in a team environment. Collaborative research experience that resides at the interface between organic/physical chemistry and life science would be ideal. Job responsibilities include: develop novel technologies from enzymes/biochemicals for application in cleaning and household care products; develop screening tools in micro-, mini-, and full-scale for selection of best technology for the application; develop a solid mechanistic understanding of the enzyme/biotechnology in our products with particular emphasis on understanding the relationship between structure and function; and characterization and performance asessment of technologies in a product matrix. Contact: Ron Webb, Ph.D., Manager, Doctoral Recruiting & University Relations, The Procter & Gamble Company, Cincinnati, OH.

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Critical Path, Inc. Research Scientist. Responsibilities include writing and reviewing stability protocols and reports to support investigational and global registration filings through the application of worldwide stability guidelines; writing and reviewing technical memos; analyzing data; and presenting accumulated stability data for review. The candidate will need good follow up, interpersonal and communication skills, and will need to work closely with other departments and in team settings. Requirements: Minimum BS degree in a science area such as biology, pharmacy, or chemistry with 6-8 years of experience, or MS with 2-8 years of experience in writing stability protocols for investigational or registration studies and aptitude and experience in data analysis. Strong technical report writing and organizational skills are essential. Knowledge and experience in using IBM compatible computers and WORD are required. Understanding and knowledge of pharmaceutics, the development process, and regulatory stability guidelines are also required. Familiarity with laboratory testing and procedures is desired. The candidate must also be able to manage multiple large projects simultaneously and be able to plan and deliver the required documents on the due dates. Please forward resumes of interest to: bhorvat@criticalpathinc.net. Beverly Horvat, Critical Path, Inc., 110 Fort Couch Road, 3rd Floor, Pittsburgh, PA 15241, Phone 412-851-4144 X16, Fax 412-851-5409.

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FACULTY POSITIONS/TEMPORARY FACULTY/ACADEMIC POSITIONS

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The Department of Chemistry at Illinois Wesleyan University invites applications for two non-tenure-track positions (pending budgetary approval), beginning Fall 2005. Candidates should possess a Ph.D. in chemistry (A.B.D. considered) and be interested in teaching in an ACS-accredited undergraduate department that emphasizes close faculty-student interaction. At least one of the positions will be filled by an organic chemist. Teaching responsibilities may include general chemistry, organic chemistry and courses for non-science majors. Complete applications (a cover letter, CV, unofficial transcripts, a description of teaching philosophy and research plans) and three letters of reference should be sent to: Chemistry Search, Department of Chemistry, Illinois Wesleyan University P.O. Box 2900, Bloomington, IL 61702-2900. More information about the department and facilities is available at http://titan.iwu.edu/~chem Inquiries may be sent to: chem@iwu.edu. Review of applications will begin immediately and continue until the position is filled. Illinois. For further information see our jobs web page at: http://www.iwu.edu/~iwujobs.

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POSTDOCTORAL POSITION AND/OR JOBS

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None Available for this Newsletter

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Please submit all newsletter information or address changes to: goldade@chem.wisc.edu or 262-0293. Thank You.

DETAILS ARE AVAILABLE IN ROOM 1146.

NEXT NEWSLETTER IS ON JANUARY 3rd, 2005.