Chemistry Newsletter

UNIVERSITY OF WISCONSIN-MADISON
DEPARTMENT OF CHEMISTRY NEWSLETTER
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XXXVI - No. 38 - December 10th, 2012
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LINDA ZELEWSKI RECOGNIZED AS AN HONORED INSTRUCTOR
Linda Zelewski was recognized as an Honored Instructor by students living in University Housing for making a significant impact on their educational experience in Chemistry 104. In their nomination, students called Linda "a very dedicated teacher who has great concern for her students' success in the class. Through Learn@UW, she provides many resources for her students to better understand the course material. In addition, the chemistry demonstrations she conducts in class also facilitate our learning." This is the third time Linda has received this award. Congratulations Linda!
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STEVE MYERS NEW MACHINE SHOP SUPERVISOR
Steve Myers started in his new role as the Machine Shop Supervisor a few weeks ago, and is settling into his job now. You've undoubtedly met him if you use the Shop with any regularity, but if you haven't met him yet, please visit him and make him feel welcome. Welcome to Chemistry, Steve!
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NEWSLETTER ON CHRISTMAS VACATION
The Chemistry Newsletter will not be published during the Christmas and New Year weeks. The Chemistry newsletter will return the first week of next year, 1/07/2013. We'll publish the newsletter on the off week only if we have news that needs to be announced for that week. Please continue to submit all of your newsletter items to: goldade@chem.wisc.edu. Thanks and have a Merry Christmas and a Happy New Year!!
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2012 Dates of Finance/Department Meetings
Department/Executive Committee Meetings - Tuesdays - 1:30 PM - Room 9341 Chemistry
December 11th, 2012
February 12th, 2013
March 12th, 2013
April 16th, 2013
May 14th, 2013
Finance Committee Meetings - Tuesdays - 1:30 PM - Room 1130
December 18th, 2012
January 22nd, 2013
February 19th, 2013
March 5th, 2013
March 19th, 2013
April 2nd, 2013
April 23rd, 2013
May 7th, 2013
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SEMINARS
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Wednesday, December 12th, 2012  - Faculty Candidate Seminar, 3:30 p.m., Room 1315 Chemistry Building. Dr.Ive Hermans of Swiss Federal Institute of Technology, Zurich. "Bridging Chemistry and Reaction Engineering for Sustainable Technologies"
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Thursday, December 13th, 2012 - Materials Science Program Seminar, 4:00 p.m., Room 265, Materials Science & Engineering Building. Jeffrey Elam, Energy Systems Division, Argonne National Laboratory. "Beyond A/B/A/B: Unorthodox Pulse Sequences in Atomic Layer Deposition"
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Friday, December 14th , 2012 - ECT Seminar, 12:00 p.m., 1025 Engineering Centers Building. Thomas Kuech, ECT Graduate Student.
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Friday, December 14th, 2012 - ECT Seminar, 12:05 p.m., 102 Water Science & Engineering Lab, 660 N. Park. Tom Kuech, ECT Graduate Student. "Nanomaterial Interactions with Biological Systems"
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Monday, December 17th, 2012 -  Faculty Candidate Seminar, 3:30 p.m., Room 1315 Chemistry Building. Dr. Bingjun Xu of CalTech "Mechanistic Investigations of Surface-mediated Reactions for Heterogeneous Catalysis and Efficient Energy Conversion"
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Wednesday, December 19th, 2012 - Faculty Candidate Seminar, 3:30 p.m., Room 1315 Chemistry Building. Dr. Yogesh Surendranath of UC-Berkeley. "Controlling Holes for Efficient Solar-to-Fuels Conversion"
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Monday, February 4th, 2013 - 2012-2013 X-Ray Superuser Seminar, 12:00 p.m., Room 1220 in the new Biochemical Sciences Building on Henry Mall. Yongna Xing lab - Presenter and title TBA.
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Tuesday, February 19th, 2013 - WISL Seminar, Room 1315 Chemistry Building. Concert at Chemistry: Celebrating WISL Fellow Marc Fink's promotion to Emeritus Professor.
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Monday, March 4th, 2013 - 2012-2013 X-Ray Superuser Seminar, 12:00 p.m., Room 1220 in the new Biochemical Sciences Building on Henry Mall. Jim Keck lab - Presenter and title TBA.
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Monday, April 1st, 2013 - 2012-2013 X-Ray Superuser Seminar, 12:00 p.m., Room 1220 in the new Biochemical Sciences Building on Henry Mall. Sam Butcher lab - Presenter and title TBA.
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Monday, May 6th, 2013 - 2012-2013 X-Ray Superuser Seminar, 12:00 p.m., Room 1220 in the new Biochemical Sciences Building on Henry Mall. Presenter and title TBA.
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RECENT PUBLICATIONS
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Dichlorido{2-[(3,5-diphenyl-1H-pyrazol-1-yl-kappa N-2)methyl]pyridine-kappa N}palladium(II).
Spencer, LC; Guzei, IA*; Segapelo, TV; Darkwa, J.
Acta Crystallographica Section C-Crystal Structure Communications, 68 M317-+; 10.1107/S0108270112043119 Part 11 NOV 2012.
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Vapor-deposited alpha,alpha,beta-tris-naphthylbenzene glasses with low heat capacity and high kinetic stability.
Whitaker, KR; Ahrenberg, M; Schick, C; Ediger, MD*.
JOURNAL OF CHEMICAL PHYSICS, 137 (15):10.1063/1.4758807 OCT 21 2012.
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Human Pumilio Proteins Recruit Multiple Deadenylases to Efficiently Repress Messenger RNAs.
Van Etten, J; Schagat, TL; Hrit, J; Weidmann, CA; Brumbaugh, J; Coon, JJ*; Goldstrohm, AC.
JOURNAL OF BIOLOGICAL CHEMISTRY, 287 (43):36370-36383; 10.1074/jbc.M112.373522 OCT 19 2012.
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A Proteogenomic Survey of the Medicago truncatula Genome.
Volkening, JD; Bailey, DJ; Rose, CM; Grimsrud, PA; Howes-Podoll, M; Venkateshwaran, M; Westphall, MS; Ane, JM; Coon, JJ*; Sussman, MR.
MOLECULAR & CELLULAR PROTEOMICS, 11 (10):933-944; 10.1074/mcp.M112.019471 OCT 2012.
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Strong Contributions from Vertical Triads to Helix-Partner Preferences in Parallel Coiled Coils.
Steinkruger, JD; Bartlett, GJ; Woolfson, DN; Gellman, SH*.
Journal of the American Chemical Society, 134 (38):15652-15655; 10.1021/ja3063088 SEP 26 2012.
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Covalent Attachment of Catalyst Molecules to Conductive Diamond: CO2 Reduction Using "Smart" Electrodes.
Yao, SA; Ruther, RE; Zhang, LH; Franking, RA; Hamers, RJ*; Berry, JF*.
Journal of the American Chemical Society, 134 (38):15632-15635; 10.1021/ja304783j SEP 26 2012.
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Rapid Phosphoproteomic and Transcriptomic Changes in the Rhizobia-legume Symbiosis.
Rose, CM; Venkateshwaran, M; Volkening, JD; Grimsrud, PA; Maeda, J; Bailey, DJ; Park, K; Howes-Podoll, M; den Os, D; Yeun, LH; Westphall, MS; Sussman, MR; Ane, JM; Coon, JJ*.
MOLECULAR & CELLULAR PROTEOMICS, 11 (9):724-744; 10.1074/mcp.M112.019208 SEP 2012.
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Observations of glyoxal and formaldehyde as metrics for the anthropogenic impact on rural photochemistry.
DiGangi, JP; Henry, SB; Kammrath, A; Boyle, ES; Kaser, L; Schnitzhofer, R; Graus, M; Turnipseed, A; Park, JH; Weber, RJ; Hornbrook, RS; Cantrell, CA; Maudlin, RL; Kim, S; Nakashima, Y; Wolfe, GM; Kajii, Y; Apel, EC; Goldstein, AH; Guenther, A; Karl, T; Hansel, A; Keutsch, FN*.
ATMOSPHERIC CHEMISTRY AND PHYSICS, 12 (20):9529-9543; 10.5194/acp-12-9529-2012 2012.
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Chemical methods to interrogate bacterial quorum sensing pathways.
Praneenararat, T; Palmer, AG; Blackwell, HE*.
ORGANIC & BIOMOLECULAR CHEMISTRY, 10 (41):8189-8199; 10.1039/c2ob26353j 2012.
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Platinum(II) and gold(I) complexes based on 1,1 '-bis(diphenylphosphino)metallocene derivatives: Synthesis, characterization and biological activity of the gold complexes.
Bjelosevic, H; Guzei, IA*; Spencer, LC; Persson, T; Kriel, FH; Hewer, R; Nell, MJ; Gut, J; van Rensburg, CEJ; Rosenthal, PJ; Coates, J; Darkwa, J; Elmroth, SKC.
JOURNAL OF ORGANOMETALLIC CHEMISTRY, 720 52-59; 10.1016/j.jorganchem.2012.08.034 DEC 1 2012.
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Structural and Sequence Analysis of the Human gamma D-Crystallin Amyloid Fibril Core Using 2D IR Spectroscopy, Segmental C-13 Labeling, and Mass Spectrometry.
Moran, SD; Decatur, SM; Zanni, MT*.
Journal of the American Chemical Society, 134 (44):18410-18416; 10.1021/ja307898g NOV 7 2012.
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Copyright © 2012 Thomson ISI
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EMPLOYMENT OPPORTUNITIES
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Center for Selective C-H Functionalization. Director for Education, Outreach & Diversity (EOD). Position Summary: Reporting to the Principal Investigator and Managing Director of the Center for Selective C-H Functionalization, this position is responsible for leading all Center broader impact efforts in education, public outreach and broadening participation.
Essential Duties & Responsibilities: As Director, the position will entail:
     •    Creating and implementing creative chemistry EOD programs from the ground up
     •    Following through with proposed EOD programs in the Phase II funded proposal including, but not
          limited to:
          •    Assisting in hire, working with, and helping mentor Communicating Chemistry
               Post-Doctoral position
          •    Coordinating student exchange program across Center sites
          •    Working with faculty on development of online Organic Pedagogical Electronic Network
          •    Establishing undergraduate summer research positions
          •    Maintaining existing and establishing new grad school prep clubs at Minority Serving
               Institutions
          •    Recruitment of new minority students/post-docs/faculty into Center and into the larger field
               of chemistry
          •    Developing assessment tools for implemented programs
     •    Developing a relationship with students, post-docs and faculty within the Center and working with
          them to implement programs
     •    Unifying individual activities at different Center sites into larger programmatic structure
     •    Attending Center meetings and leading EOD bimonthly meetings.
     •    Presenting on progress yearly at Annual symposia, in regular reports and at all site visits by NSF
     •    Creating and managing a yearly budget of ~$300,000
     •    Seeking out additional funding opportunities for EOD programs of interest
Qualifications: To perform this job successfully, an individual must be able to perform each essential duty satisfactorily. The requirements listed below are representative of the knowledge, skill, and/or ability required. Reasonable accommodations may be made to enable individuals with disabilities to perform the essential functions. Education And/or Experience: The ideal candidate will possess a combination of the following education and/or equivalent experience:
     •    Master's degree in chemistry or physical sciences; PhD and experience in organic chemistry
          preferred.
     •    Two years experience in education or outreach activities preferred
     •    Demonstrated experience in teaching and/or science writing for public audiences of diverse
          backgrounds, ages and degree of knowledge; advanced understanding of English grammar and
          proofreading.
Knowledge, Skills & Abilities:
     •    Ability to multitask, successfully handling multiple projects simultaneously
     •    Thorough understanding of chemistry and informal science education
     •    Excellent verbal and written communication skills
     •    Ability to work successfully and independently on open ended projects without outlined deadlines
     •    Ability to effectively develop outreach programs using a variety of methods to communicate
          chemistry concepts to different audience(s).
     •    Ability to write clearly, concisely and imaginatively.
To Apply: Please email a cover letter and CV to: chemsearch@emory.edu, with CCHF EOD Director as the subject line. Please include the names of two referees who could comment on your qualifications for this position.
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FACULTY POSITIONS/TEMPORARY FACULTY/ACADEMIC POSITIONS
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Department of Chemistry and Biochemistry, University of Maryland, Baltimore County. Applications from outstanding scientists are invited for the position of Chair of the Department of Chemistry and Biochemistry at UMBC. The Department offers graduate and undergraduate degrees in both chemistry and biochemistry with a highly cross-disciplinary and interactive group of faculty and lecturers. Cutting-edge research is carried out by post-doctoral fellows, Ph.D., MS and undergraduate students working in excellent laboratory facilities in a recently renovated building. The University is strategically situated on a suburban campus in the intellectually and culturally vibrant Baltimore-Washington corridor, which enhances the dynamic educational and research opportunities afforded by its diversity, intermediate size and world-class infrastructure. The Chair will be expected to provide vigorous leadership toward expanding the department's current research profile and directing the next stage of departmental growth. Applications are invited from internationally recognized scholars in any area who have a commitment to superior research and innovative teaching at both the graduate and undergraduate levels. Applicants should submit a letter of application, a curriculum vitae and the names of three persons who can be contacted for supporting letters to: Chair, Faculty Search Committee, Department of Chemistry and Biochemistry, University of Maryland, Baltimore County, 1000 Hilltop Circle, Baltimore, MD 21250. Electronic submissions can be made to: chemsearch@umbc.edu. Applications will enter the review process as soon as they are received and consideration of applications will continue until the position is filled.
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3-Tenure Track Positions. Chemistry Department, University of Connecticut. The Department of Chemistry in the College of Liberal Arts and Sciences invites applications for three Assistant/Associate/Full Professor tenure-track positions. The positions will be in the Green Emulsions, Micelles and Surfactants (GEMS) Center of the Department of Chemistry. Researchers involved with the synthesis, characterization, modeling, and applications of emulsions, micelles, and surfactants, interpreted in the broadest sense, will be considered. Minimum Qualifications: Applicants must have a Ph.D. (or equivalent) in Chemistry or a closely related field in hand by the time the appointment begins. Outstanding record of research accomplishments in Chemistry or a related field and Strong oral and written communication skills are needed. Qualified applicants who can advance the diversity of our research and teaching mission may be considered for appointment at higher rank. Successful applicants will be expected to develop well-funded, nationally and internationally recognized research programs while simultaneously maintaining excellence in teaching at both the undergraduate and graduate levels. A complete application will include a curriculum vitae, a detailed description of research projects, and a brief statement of teaching philosophy and interests. These are nine-month, tenure-track positions starting in August 2013. Salary and rank will be determined based on qualifications. To apply, please visit the University's Husky Hire online application system at: http://www.jobs.uconn.edu. A cover letter, curriculum vitae, a detailed description of research plans, and a statement of teaching philosophy/interests can be uploaded to this website. In addition, please arrange for three confidential letters of recommendation to be sent to: Ms. Emilie Hogrebe, University of Connecticut, Department of Chemistry, 55 North Eagleville Road, Unit 3060, Storrs, CT 06269-3060 or to: e.hogrebe@uconn.edu. Assuming budget approvals, screening of applications will proceed immediately and will continue until the positions are filled. Please include the search number with all correspondence. Search # 2013333.
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POSTDOCTORAL POSITIONS AND/OR JOBS
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Bioengineering Doctoral Studies in Protein Drug Discovery& Development for Biochemistry & Life Sciences Majors. The lab of Dr. Pete Heinzelman in the University of Oklahoma College of Engineering has biopharmaceutical engineering research opportunities for students who will be completing Biochemistry or Life Sciences undergraduate degrees and would like to translate these skill sets to earning a Ph.D. in Bioengineering. Students need not have taken engineering courses; we are focused on what new team members will achieve going forward rather than prior classroom experience. We apply the methods of protein engineering in developing novel biopharmaceuticals that will improve the lives of persons afflicted with Alzheimer's Disease (AD), cancer, diabetes, and other conditions. Several facets of this research are enabled by our utilization of high-throughput screening platforms for performing in vitro laboratory directed evolution of new proteins with increased therapeutic efficacy. Pursuit of these objectives takes place in an intense and invigorating environment of discovery and possibility modeled after the research settings that I have been fortunate to experience during my time as a postdoctoral fellow at Caltech, a graduate student at MIT, and an undergraduate at The University of Wisconsin-Madison. We are seeking to add doctoral graduate student team members who want to help grow this environment while preparing themselves to be successful in realizing whatever their visions for life after graduate school might be. There are opportunities for graduate students to develop as researchers while helping us realize our goals in the context of four well-defined projects, with the door always open to turning a new idea into that next research initiative: Blood Brain Barrier-Traversing Alzheimer's Disease Therapeutics; Whole Cell Therapeutics for Cancer Therapy; Tumor-Sensing Proteins For Chemotherapeutic Delivery; Orally Available Protein Therapeutics. As the leader of this team, I emphasize student professional development and place high priority on "coaching" and encouraging students to quickly become independent researchers and idea synthesizers. This development is further fostered by making industrial internships, participation in conferences and involvement in collaborative research key parts of team member graduate study experiences. I also believe that appreciation for high level performance should be reflected in student compensation. As such, I make an extra effort to ensure that graduate student team members receive stipends and fellowships summing to or exceeding National Science Foundation Graduate Research Fellow allowances. We are eager to add motivated students who will begin in the University of Oklahoma Bioengineering doctoral program in May or August of 2013. I will facilitate fast-tracking the applications and admissions process and ask that students who wish to learn more about opportunities with our team not put off contacting me via email: proteinpete@gmail.com. I'm excited about the multiple good fits for new students in this research group and eager to hear from you!
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Postdoctoral Positions. Hahn lab, University of North Carolina - Chapel Hill. Departments of Pharmacology, Medicinal Chemistry, and Lineberger Cancer Center. We are seeking postdoctoral fellows to develop and apply novel approaches for in vivo manipulation and imaging of signaling. We are a multidisciplinary team using protein engineering, organic chemistry, and novel microscopy techniques to study the dynamics of signaling networks in living cells and animals.  We seek postdoctoral fellows to design novel biosensors, molecules for photomanipulation of protein activity, and engineered allosteric activation of signaling pathways. Other positions focus on the flow of information through signaling networks controlled by spatio-temporal dynamics, and involve interactions with groups developing models of network behavior and computational tools to understand and model imaging data. See the Hahn lab web site for more  information about our work and the exciting collaborative environment at UNC. (hahnlab.com). See also Gulyani et al. Nature Chem. Bio 7:437 p437; Karginov et al. Nature Biotech 28(7) p743; Yoo et al. Developmental Cell 18 p226; Wu et al. Nature 461 p104; and Machacek et al Nature 461 p99. Chemical Biology. We seek postdoctoral fellows experienced  in the design and execution of complex multi-step organic syntheses. This position offers the opportunity for an organic chemist to move into a new area of research, focusing on projects that combine organic synthesis and molecular biology to develop new tools for the imaging and manipulation of signaling pathways in vivo.  There will be multiple opportunities to apply your new tools in biological studies. Biophysics and imaging. We are developing novel biophysical techniques based on lifetime imaging, single molecule imaging and correlation microscopy to study signaling dynamics in living cells. These projects will require a background in mathematics, physics or engineering, and ideally an understanding of microscopes, lasers, and/or programming for microscope automation. This is a collaboration with Enrico Gratton of the Laboratory of Fluorescence Dynamics (http://www.lfd.uci.edu/). GEF- GTPase signaling networks. These positions are for postdocs interested in protein engineering and/or the spatio-temporal dynamics of signaling networks.  Projects focus on a) developing novel biosensor approaches for signaling upstream and downstream of GTPases b) methods for control of such  molecules in vivo, and/or c) use of these  tools to dissect the spatio-temporal dynamics of signaling networks controlling cell  polarization and trans-endothelial migration. We will interact closely with Dr. Gaudenz Danuser developing network models and computational approaches to derive information re the spatio-temporal dynamics of signaling from imaging data http://lccb.hms.harvard.edu/, and with Drs. Keith Burridge http://www.med.unc.edu/cellbiophysio/faculty/burridge and with John Sondek of UNC http://www.med.unc.edu/pharm/sondeklab/, who study the biology and structural biology of GEFs and GTPases. Applications in vivo will be carried out with Dr. Anna Huttenlocher, examining TEM in zebrafish models http://medmicro.wisc.edu/people_faculty.php. To apply, please send a CV  to Klaus Hahn at: khahn@med.unc.edu.
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Please submit all newsletter information or address changes to: goldade@chem.wisc.edu or 262-0293. Thanks.
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DETAILS ARE AVAILABLE IN ROOM 1146.
NEXT NEWSLETTER IS ON JANUARY 7th, 2013