Chemistry Newsletter - 06/10/2002

 

University of Wisconsin-Madison

Department of Chemistry Newsletter


XXVI - No. 22 June 10th, 2002

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Department and Finance Committee Meeting Schedule

Department Meetings --- Tuesdays - 1:30 PM - Room 8335 Chemistry

None Scheduled at this Time

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Finance Committee Meetings --- Tuesdays ---1:20 PM - Chair's Office

 

None Scheduled at this Time

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SEMINARS

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Tuesday, July 2nd, 2002 - Organic Chemistry Seminar, 3:30 p.m., Room 1315 Chemistry Building. Professor Masahiro Hirama, Tohoku University, Sendai, Japan.

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Tuesday, October 1st, 2002 - Organic Chemistry Seminar, 3:30 p.m., Room 1315 Chemistry Building. Professor Steve Diver, SUNY-Buffalo.

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Tuesday, October 15th, 2002 - Organic Chemistry Seminar, 3:30 p.m., Room 1315 Chemistry Building. Professor Eric Simanek, Texas A & M.

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RECENT PUBLICATIONS

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Ringeisen BR; Muenter AH; Nathanson GM.

Collisions of HCl, DCl, and HBr with liquid glycerol: Gas uptake, D -> H exchange, and solution thermodynamics.

JOURNAL OF PHYSICAL CHEMISTRY B 2002, Vol 106, Iss 19, pp 4988-4998.

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Ringeisen BR; Muenter AH; Nathanson GM.

Collisions of DCl with liquid glycerol: Evidence for rapid, near-interfacial D -> H exchange and desorption.

JOURNAL OF PHYSICAL CHEMISTRY B 2002, Vol 106, Iss 19, pp 4999-5010.

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Ludwig R; Weinhold F.

Quantum Cluster Equilibrium theory of liquids: Isotopically substituted QCE/3-21G model water.

ZEITSCHRIFT FUR PHYSIKALISCHE CHEMIE-INTERNATIONAL JOURNAL OF RESEARCH IN PHYSICAL CHEMISTRY & CHEMICAL PHYSICS 2002, Vol 216, pp 659-674.

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Ranade MR; Navrotsky A; Zhang HZ; Banfield JF; Elder SH; Zaban A; Borse PH; Kulkarni SK; Doran GS; Whitfield HJ.

Energetics of nanocrystalline TiO2.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 2002, Vol 99, pp 6476-6481.

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West R.

Multiple bonds to silicon: 20 years later.

POLYHEDRON 2002, Vol 21, Iss 5-6, pp 467-472.

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Bach A; Hutchison JM; Holiday RJ; Crim FF.

Vibronic structure and photodissociation dynamics of the (A)over-tilde state of jet-cooled ammonia.

JOURNAL OF CHEMICAL PHYSICS 2002, Vol 116, Iss 21, pp 9315-9325.

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Copyright © 2002 Institute for Scientific Information

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EMPLOYMENT OPPORTUNITIES

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New developments at Provid Pharmaceuticals, a company established in 2001 to pursue chemistry-based drug discovery. We are now moving forward with significant collaborations, research programs, and major strategic partnerships, and we are currently building our chemistry group. Provid is currently recruiting Ph.D. and B.S./M.S. chemists at all levels to join us in our research to identify small molecule drugs for the treatment of autoimmune and infectious diseases, and to work in our corporate collaborations. In addition to entry level positions, we are seeking experienced candidates, typically with 5+ years experience in pharmaceutical research for leadership roles. We are interested in synthetic and medicinal chemists with a range of experience to pursue many types of drug targets. The focus for several of our targets is the exciting core technology in peptide mimetics developed by Professors Hirschmann and Smith that we have licensed from the University of Pennsylvania. Recently, we have established a strategic partnership with SEQUENOM Inc., a leading genomics company that has identified multiple disease genes and drug targets. In this collaboration, Provid will pursue leads in cardiovascular disease using our technology platform. We have also developed a relationship with Hikal, Ltd. in Bangalore, India, to support our chemistry and have ongoing relationships with academic groups at Harvard and Rutgers. Provid is located in Piscataway, NJ near the Rutgers University campus in a suburban area of New Jersey. As part of our strategy, we have licensed from Penn a broad portfolio of the patents of Profs. Smith and Hirschmann in peptide mimetics. We plan to develop the pyrrolinone and carbohydrate mimetics that they have discovered for a number of potential targets. We would appreciate any assistance you can give us in identifying candidates who have the talents and interest to work in an emerging company in the field of drug discovery. Some additional information about Provid is found on our web site: http://www.providpharma.com, including information on job openings and resume submission.

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Kansas State University, Senior Scientist, Department of Chemistry NMR Spectroscopist. The Department of Chemistry invites application for a Departmental NMR Spectroscopist beginning as soon as possible. The Department has Varian 400 and 200 MHz NMR spectrometers and a Tecmag 300 MHz solid state NMR spectrometer. The successful candidate will be responsible for maintaining and scheduling these instruments, training graduate students and providing technical support to users. A Ph.D. in NMR spectroscopy and experience with UNIX based operation system administration are required. Knowledge about solid state NMR and RF electronics are preferred and excellent communication and organizational skills are necessary. The Departmental NMR Spectroscopist is encouraged to take the opportunity to collaborate in research with our departmental research groups. Informal enquiries are welcome to: Dr. Ralf Warmuth, Tel: (785) 532 6684; e-mail: warmuth@ksu.edu; FAX: 785-532-6666. Applicants should submit a letter of application; a complete curriculum vita; copies of transcripts from graduate studies; and arrange to have three letters of recommendations sent to: Dr. Ralf Warmuth, Chair Departmental NMR Spectroscopist Search Committee, Department of Chemistry, Kansas State University, Manhattan, Kansas, 66506-3701. Screening will commence July 1, 2002 and will continue until a suitable candidate is found. Details of the department can be found at http://www.ksu.edu/chem.

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FACULTY POSITIONS/TEMPORARY FACULTY/ACADEMIC POSITIONS

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None For This Newsletter

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POSTDOCTORAL POSITION AND/OR JOBS

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University of Maryland, Postdoctoral Research Associate: The research includes determination of the three-dimensional conformation and dynamics of complex polysaccharides and oligosaccharides from pathogenic bacteria. Practical applications of the research are related to development of bacterial polysaccharide vaccines. Methods will emphasize heteronuclear multidimensional NMR spectroscopy including measurement of scalar and dipolar coupling of 15 N and 13C enriched samples. Analysis will require computer molecular modeling and molecular dynamics simulation. Excellent NMR instrumentation and computer facilities are available including spectrometers at 500, 600 and 800 MHz including a recenty purchased high-sensitivity cryoprobe. The NMR methods available exploit heteronuclear scalar coupling as well as residual dipolar coupling in solutions weakly oriented by liquid crystals. A scheme for enrichment in 13C (or 15N ) for cell wall polysaccharides from viridans streps and also for the capsular polysaccharides of vibrio cholerae provides a source of biologically active polysaccharides and oligosaccharides for these NMR experiments. Recently developed methods for computer molecular modeling will be combined with molecular dynamics simulation for interpretation of the NMR data. Appointments are made for a period of one year but are renewable by mutual agreement. For reprints of recent papers, see: http://www.research.umbc.edu/~bush/ Candidates should send C.V. and three letters of recommendation to: C. Allen Bush, Department of Chemistry and Biochemistry, University of Maryland Baltimore County, 1000 Hilltop Circle, Baltimore, MD 21250, e-mail: bush@umbc.edu.

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University of Nebraska, Postdoctoral Research Associate: A postdoctoral position is available immediately to develop new approaches to catalyst discovery and reaction optimization based on our ISES (In situ enzymatic screening) concept. The position will also involve the specific development and application of synthetic methodology in the organophosphorus area. For a discussion of ISES see: http://pubs.acs.org/isubscribe/journals/cen/80/i21/html/8021sci2.html. A list of recent publications from the laboratory can be found at: http://www.chem.unl.edu/dbb/. The initial appointment will be for one year, renewable upon mutual consent, with a salary commensurate with experience. Interested candidates should contact: Prof. David Berkowitz (University of Nebraska) at: dbb@unlserve.unl.edu.

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Professor Ken Whitmire of Rice University anticipates a new postdoctoral position to be available in his research group as of July 1, 2002. The position requires excellent skills in the handling of air sensitive materials (Schlenk and vacuum line techniques) as well as in the synthesis and characterization of inorganic and organometallic compounds. The project involves catalysis and materials applications of heteronuclear metal clusters. A good knowledge of infrared spectroscopy, multinuclear nuclear magnetic resonance spectroscopy, mass spectrometry, x-ray diffraction, UV-visible spectroscopy plus other standard analytical characterization methods is essential to the success of this work. The candidate should demonstrate good oral and written communication skills. Details of our research program may be found at http://www.ruf.rice.edu/~whitmir. Interested persons should send a curriculum vitae and publications list to me electronically and should arrange for three supporting letters of recommendation to be sent to: Kenton H. Whitmire, Chair and Professor of Chemistry, Department of Chemistry, MS60, Rice University, 6100 Main Street, Houston, TX 77005-1892, Phone: 713-348-5650, Departmental Fax: 713-348-5155, Organometallics. Contact Information: Emily Heitman, Journal Administrator, Tel: 713-348-5863, Fax: 713-348-5652, Toll-Free Fax for Reviews Only: 888-245-3979.

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Kansas State University. Two postdoctoral positions at the rank of research associate are available immediately to study ferroelastic and ferroelectric domain switching, crystal growth, crystallography, and molecular recognition phenomena in organic crystals and inclusion compounds. One position requires strong background in Solid State NMR spectroscopy; the researcher would be responsible for the operation and maintenance of a 300 MHz NMR instrument dedicated to solid state experiments such as MAS, 2 H NMR, single crystal NMR, and REDOR. The ideal applicant would have extensive experience in a variety of solid state NMR experiments as well as a broad training in solid state organic chemistry. The second position requires a strong background in Solid State Organic Chemistry; the project will focus on cooperative phenomena and domain switching in ferroelastic and ferroelectric inclusion compounds. Specific expertise in the areas of stress-strain relationships in crystals, diffraction (X-ray and neutron), polarized spectroscopy and microscopy, crystal growth, and atomic force microscopy would be extremely beneficial. In each position, experience and interest in organic synthesis would also be very helpful. The successful applicants will have a Ph.D. in Chemistry or related discipline. Duration of the position would be for at least one year, and preferably for two years. Salary will be commensurate with experience and background. Send c.v. and names and addresses of three reference to: Prof. Mark D. Hollingsworth, Chemistry Dept., 111 Willard Hall, Kansas State University, Manhattan, KS 66506; ph.: 785-532-2727, fax: 785-532-6666, e-mail: mdholl@ksu.edu.

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Please submit all newsletter information or address changes to: goldade@chem.wisc.edu or 262-0293. Thank You.

DETAILS ARE AVAILABLE IN ROOM 1146.

NEXT NEWSLETTER IS ON JUNE 24th, 2002.