Chemistry Newsletter - 06/08/2004

 

University of Wisconsin-Madison

Department of Chemistry Newsletter


XXVIII - No. 21 June 8th, 2004

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Snout Out 2004

The annual Chemistry Department picnic, the "Snout-Out", is scheduled for Hoyt Park on Saturday, August 28. Please mark your calendar, and we will provide more details as the time approaches. Chris Elles - Graduate Student-Faculty Liaison Committee (GSFLC)

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Department and Finance Committee Meeting Schedule

Department Meetings - Tuesdays - 1:30 PM - Room 9341 Chemistry

TBA

Finance Committee Meetings - Tuesdays - 1:20 PM - Chair’s Office

TBA

Executive Committee Meetings - Tuesdays - 1:20 PM - Room 9341

TBA

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SEMINARS

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Analytical Seminar abstracts/announcements can be found at: http://analytical.chem.wisc.edu/analytical/writings/Seminars/seminars.html.

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Physical Chemistry Student Seminar abstracts/announcements can be found at: http://www.chem.wisc.edu/physical/Home.html.

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Recent Publications

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Nelana SM. Darkwa J. Guzei IA. Mapolie SF.

Ethylene polymerization catalyzed by substituted pyrazole nickel complexes.

Journal of Organometallic Chemistry. 689(10):1835-1842, 2004 May 15.

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Ivanov SA. de Silva N. Kozee MA. Nichiporuk RV. Dahl LF.

Synthesis and structural/theoretical (DFT) analysis of the geometrically unprecedented Au-Pt cluster, Pt7(mu(2)-CO)8(PPh3)(4)(mu(4)-AuPPh3)(2): Structure-to-synthesis appraisal concerning its formation.

Journal of Cluster Science. 15(2):233-261, 2004 Jun.

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Lawrence CP. Skinner JL.

On the mode-coupling theory of vibrational line broadening in near-critical fluids.

Journal of Chemical Physics. 120(18):8651-8661, 2004 May 8.

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Brunold TC.

Combined spectroscopic/computational studies of metal centers in proteins and cofactors: Application to coenzyme B-12.

Chimia. 58(4):186-193, 2004.

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Copyright © 2004 Thomson ISI

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EMPLOYMENT OPPORTUNITIES

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The University of Birmingham is recruiting eight highly motivated individuals to an ultra high field NMR facility which includes Varian 900, 800, 600 and 500 MHz and Bruker 500 MHz NMR systems, and to Prof Michael Overduin's protein expression and analysis laboratory in the Institute for Cancer Studies. The Henry Wellcome Building for Biomolecular NMR Spectroscopy has been established by The Wellcome Trust as a new national NMR facility for the United Kingdom (see http://www.cancerstudies.bham.ac.uk/Research/NMR/). The positions are supported by the BBSRC, Cancer Research UK and Wellcome Trust. Birmingham is a vibrant cultural city located near Stratford and the Cotswolds, and is close to London and Oxford.

The NMR Technician will have responsibility for the maintenance and service of the NMR systems. The ideal candidate will hold a B.Sc. in engineering or the physical sciences, and have experience with maintaining of NMR spectrometers or other analytical instrumentation.

The six Postdoctoral Fellows will study the structure, interactions and mechanisms of proteins involved in signal transduction, membrane trafficking and cancer biology. Appointees will have access to the NMR spectrometers and will develop collaborative structural biology projects. The ideal candidates should have a Ph.D. degree, excellent communication and presentation skills, and demonstrated experience in the area of protein NMR. This includes acquisition and analysis of multi-dimensional NMR data, implementation of NMR pulse sequences, and interpretation of NMR data for structure determination and ligand interactions.

The Laboratory Technician will operate the protein expression and analysis facility, and will be involved in collaborative protein structure/function studies. The ideal candidate will hold a bachelor's degree or equivalent, and have practical experience in molecular biology and protein biochemistry.

Application forms are available at: http://www.personnel.bham.ac.uk/vacancies and are returnable by June 15 (NMR technician) or 16 (other posts). Please quote job reference number. Details should be sent to: Personnel Services, The University of Birmingham, Edgbaston, Birmingham B15 2TT, Tel: +44(0)121 415 9000. Inquires should be sent to M.Overduin@bham.ac.uk. Salary commensurate with education and experience. Positions start beginning mid-2004.

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Pfizer Global Research and Development has an opening for a Post-doc in biomolecular NMR at their La Jolla facility. We are seeking a Ph.D. to do biomolecular NMR of pharmaceutically relevant targets. The individual will support project team(s) that have expressed interest in structure, dynamics, and/or information on binding modes between small therapeutically active ligands and the protein target. The successful candidate will initiate and complete one or more of these studies and in turn, provide projects the high quality data that is required for making decisions in the drug discovery process. Publication or presentation of results for many projects will be strongly encouraged. The ideal candidate will have NMR experience with larger proteins, protein complexes and/or RDC measurements for structure determinations. Experience with Varian spectrometers is desirable; however both vendors instruments may be used for some projects. Strong communication skills and team focus needed. The position is for one year, renewable for a maximum of 2 years and offers a competitive compensation package that includes full benefits and relocation. For further information please reply to: Cathy Moore, e-mail: cathy.d.moore@pfizer.com or apply on at: http://www.pfizer.com/subsites/pgrd/find/index.html using the reference code: 25May0429710.

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FACULTY POSITIONS/TEMPORARY FACULTY/ACADEMIC POSITIONS

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The Department of Chemistry and Physics at Southwestern Oklahoma State University in Weatherford, Oklahoma (located approximately 70 miles west of Oklahoma City on Interstate 40) has two one-year positions available beginning in Fall 2004. The teaching load will include General and/or Organic Chemistry lecture and lab in an ACS-certified program. A Master's degree in chemistry is required, ABD or PhD preferred. At least one of these positions will be converted to a full-time position for the 2005-06 academic year. To apply, one should submit a cover letter referencing Postions 04-F038 and 04-FO39, unofficial transcripts, and the names, addresses, and phone numbers of three references to: the Office of Human Resources, SWOSU, 100 Campus Drive, Weatherford, OK 73096 or email application materials to Michelle.Harvey@swosu.edu.

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POSTDOCTORAL POSITION AND/OR JOBS

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Professor John B. Wiley currently has a postdoctoral position available in my research group for one year with possible renewal for a second year. The ideal candidate would be familiar with solid-state synthesis and Rietveld refinement techniques. Additional experience with handling air sensitive samples and/or magnetic structure refinements would be a definite plus. To learn more about the general thrust of our research, candidates are encouraged to review the publications: J. Am. Chem. Soc. 1999, 121, 10743, Inorg. Chem., 2001, 40, 710, Inorg. Chem. 2002, 41, 3385, Chem. Mater. 2003, 15, 1480, and J. Solid State Chem. 2003, 175, 88. Interested candidates should send their CV to John Wiley at: jwiley@uno.edu. Professor John Wiley, Department of Chemistry and the Advanced Materials Research Institute, University of New Orleans, New Orleans-LA 70148-2820.

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University of Pennsylvania School of Medicine. Department of Biochemistry and Biophysics, 905B Stellar-Chance Laboratories, 422 Curie Boulevard, Philadelphia, PA 19104-6059, Phone: 215-898-8029, Joseph T. Jarrett, Ph.D., Associate Professor. Postdoctoral Position-Enzymology/Bioinorganic Chemistry A postdoctoral position is available in my laboratory in the Department of Biochemistry and Biophysics at the University of Pennsylvania. My laboratory has broad interests that include the mechanisms of radical enzymes, the trafficking and assembly of iron-sulfur clusters in bacteria, metalloenzyme design and evolution, and general topics related to enzyme catalysis. The focus of the current open position is on using isotopic and spectroscopic methods to probe the formation of discrete catalytic intermediates during turnover of the adenosylmethionine-dependent radical enzyme biotin synthase (recent references below). These studies will utilize rapid-reaction kinetics (stopped-flow, rapid quenched-flow, rapid freeze-quench techniques) together with UV/visible, EPR, ENDOR, and mass spectrometry to correlate changes in the iron-sulfur cofactors with conversion of substrates to discrete observable intermediates. Prior experience with any of these techniques, or with the anaerobic manipulation of metalloenzymes, is preferred; however, applications are welcome from individuals with general enzymology experience that are interested in learning bioinorganic chemistry. The current position is fully funded through a grant from the NIH, but applicants will be encouraged to apply for independent fellowships to further their career prospects. The Department of Biochemistry and Biophysics is located in the Stellar-Chance Laboratories, a new state-of-the-art biomedical research building located in the heart of the University of Pennsylvania Medical Center in Philadelphia. The department houses modern EPR, NMR, and x-ray crystallography facilities, and is located within 3 blocks of the Chemistry and Biology Departments and the Wistar Institute, where additional instrumentation is available as needed. The University of Pennsylvania is surrounded by the tree-lined residential neighborhood of University City, approximately one mile from downtown Philadelphia, and the campus has train and subway stations that provide rapid access to much of suburban Philadelphia. Applicants should send a C.V. and contact information for 3 references to: Dr. Joseph T. Jarrett, Department of Biochemistry & Biophysics, University of Pennsylvania, Philadelphia, PA 19104-6059, or by email to: jjarrett@mail.med.upenn.edu.

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Please submit all newsletter information or address changes to: goldade@chem.wisc.edu or 262-0293. Thank You.

DETAILS ARE AVAILABLE IN ROOM 1146.

NEXT NEWSLETTER IS ON JUNE 21st, 2004.