Chemistry Newsletter - 01/14/2002

 

University of Wisconsin-Madison

Department of Chemistry Newsletter


XXVI - No. 2 January 14th, 2002

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Department and Finance Committee Meeting Schedule

Department Meetings --- Tuesdays - 1:30 PM - Room 8335 Chemistry

February 12th, 2002 March 12th, 2002 April 9th, 2002 May 14th, 2002

Finance Committee Meetings --- Tuesdays ---1:20 PM - Chair's Office

January 15th, 2002 February 5th, 2002
February 19th, 2002 March 5th, 2002 March 19th, 2002 April 2nd, 2002
April 16th, 2002 May 7th, 2002 May 21st, 2002

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**Department meeting and the executive committee meeting on Tuesday, January 22 at 1:30 in room 8335.**

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SEMINARS

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Tuesday, January 15th, 2002 - Analytical Seminar - 9:00 a.m., Room 2373 Chemistry Building. Ph.D. Defense by Ryan B. Parks, UW-Madison Graduate Student (Burstyn Group). "Heme as an Allosteric Regulator in Cooa and Cystathionine B-synthase"

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Thursday, January 17th, 2002 - Organic Seminar, 11:00 a.m., Room 1315 Chemistry Building. Professor Vichai Reutrakul, Mahidol University.

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Tuesday, January 22nd, 2002 - Physical Chemistry Seminar, 11:00 a.m., Room 1315 Chemistry Building, Alexei Stuchebrukhov, UC Davis. "Electron and proton transfer in membrane proteins. Quantum mechanics and biological energy transduction"

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Wednesday, January 23rd, 2002 - Inorganic Seminar, 1:20 p.m., Room 1315 Chemistry Building. Bob Clark, Graduate Student.

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Tuesday, January 29th, 2002 - Physical Chemistry Seminar, 11:00 a.m., Room 1315 Chemistry Building, Christoph Naumann, Indiana Univ. Purdue Univ. Indianapolis. "Obstructed Diffusion Of Proteins And Lipids In Bioartificial Membranes Studied At The Single Molecule Level"

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Tuesday, January 29th, 2002 - Organic Seminar, 3:30 p.m., Room 1315 Chemistry Building. Professor Cathleen Crudden, University of New Brunswick. "Asymmetric Synthesis With Homogeneneous and Heterogenized Transition Metal Catalysts"

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Tuesday, February 5th, 2002 - Organic Seminar, 3:30 a.m., Room 1315 Chemistry Building. Professor Hicham Fenniri.

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Tuesday, February 12th, 2002 - Physical Chemistry Seminar, 11:00, Room 1315 Chemistry Building. Dvarajan Thirumalai, University of Maryland. "Chaperonin-Mediated Protein folding"

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Monday, March 4, 2002 - Physical Chemistry Ferry Lectures, 3:30 p.m., Room 1315 Chemistry Building, Professor Jacob Klein, University of Oxford. "Rheology Under Confinement"

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Tuesday, March 5, 2002 - Physical Chemistry Ferry Lectures, 11:00 a.m. Room 1315 Chemistry Building. Professor Jacob Klein, University of Oxford."Polymer Brushes: From Colloidal Stabilisation to Biological Recognition"

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Tuesday, April 23, 2002 - Physical Chemistry McElvain Seminar, 11:00 a.m., Room 1315 Chemistry Building, Professor Richard Zare, Stanford. "Prospects for Advances in Micro and Nanoscale Chemical Analysis"

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We invite your nominations to select scholar-teachers as Fellows in the Teaching Academy at the University of Wisconsin-Madison. Nominees may be any members of the faculty or of the academic staff involved in undergraduate, graduate, or outreach teaching. Nominees should be outstanding university educators who are concerned about teaching and enriching the learning environment at this university. The Academy particularly welcomes individuals who have demonstrated excellence through classroom innovation, program development, grant funding, publications, presentations, or committee work related to teaching or learning. The Faculty Senate established the Teaching Academy of the University of Wisconsin-Madison in 1993. Alone and in concert with other campus-based bodies, the Teaching Academy strives to enhance the quality of education. In monthly meetings, it develops strategies for highlighting the important place of teaching at a large research University, promoting a culture that supports and rewards excellent teaching, and encouraging serious reflection on critical issues that concern teaching and learning in a university setting. The work of the Academy is also done within its task forces. At present, there are five task forces: 1) Task Force on Celebrating Effective Teaching, 2) Task Force on the Peer Review of Teaching, 3) Task Force on Information Technology, 4) Task Force on the Uniqueness of Teaching on a Research Campus, and 5) Task Force on the Scholarship of Teaching. Members of the Academy are active in one or more of the task forces. We welcome your nominations of persons to be Teaching Academy Fellows in recognition of their excellence and for participation in a spirited forum for discussion, debate, and enhancement of teaching. Nomination procedures and forms can be found on the Teaching Academy's web site at http://www.wisc.edu/teaching-academy, and paper copies can be requested directly by calling the Teaching Academy office at 3-7748 or by e-mailing our project assistant, Suzanne Schier-Happell, at schierhappell@bascom.wisc.edu. The schedule of dates for the process is as follows: application deadline is March 1; notification of selection - early to mid - April; induction - April 24.

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Summer Research Experience

Interdisciplinary Program for Chemistry and Physics Undergraduates. Join us in Eugene for Summer 2002! We provide the housing, stipend and travel expenses, as well as unique laboratories and equipment for cutting edge research! You get to work alongside grad students and faculty using state-of-the-art instruments during the week, and take off for the mountains or other adventure spots on the weekends. For program information or application form, contact: Catherine Hayden, Materials Science Institute, 1252 University of Oregon, Eugene OR 97403-1252, Ph: 541-346-5898, fax: 541-346-3422, e-mail: chayden@darkwing.uoregon.edu, web: http://materialscience.uoregon.edu/Undergraduate/reu.htm. Application deadline is February 15, 2002.

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Leonard M. Rieser Research Fellowship

The Educational Foundation for Nuclear Science, publisher of The Bulletin of the Atomic Scientists, is pleased to announce that it is accepting applications for the Leonard M. Rieser Research Fellowship for the 2002-2003 academic year. The Fellowship, inaugurated two years ago, honors Leonard M. Rieser (1922-98), an accomplished physicist, activist for the peaceful resolution of conflict, and professor emeritus of Dartmouth University, who was deeply committed to investing in the ideas and the potential of young people. The Rieser Research Fellowship is intended to help students - especially those majoring in a scientific field - explore emerging or critical issues at the juncture of science, global security, and public policy. It is presented annually to students whose academic interests, extra-curricular activities, and career aspirations demonstrate an interest in the role of scientists in formulating public policy and in addressing global security challenges. The Fellowship will annually provide one-time awards of $2,500 to between three and five undergraduate students seeking to explore the connections between science, global security, and public policy (science students are especially encouraged to apply). It will be presented to students whose academic interests, extra-curricular activities, and career aspirations demonstrate an interest in the role of scientists in formulating public policy and in addressing global security policy challenges. Any undergraduate student studying at a U.S. college or university is eligible to apply for the Leonard M. Rieser Research Fellowship. The Fellowship may be used over the course of one year (12 months) to support academic research or professional development, in the United States or abroad. The Fellowship will be paid in two installments of $1,250-one made at the commencement of the Fellowship, and the second upon its conclusion and following the receipt of a project report and receipts. Specifically, the Fellowship could be used for the following purposes: To provide a stipend for an otherwise unpaid full-time internship; To provide for housing or a per diem for research conducted out of town; To underwrite the cost of travel or transportation to support academic research; For participation in or travel to professional conferences where the Fellow presents academic research; To underwrite the production costs of a special project, ranging from the making of a documentary film to laboratory work. Students must supply the following materials when applying for the Fellowship: A completed application form (available from the EFNS Web site at http://www.thebulletin.org/fellowship.html or by writing to the address below); An 800-1,000 word narrative proposal describing the applicant's intended use of the Fellowship. Students must provide substantiation of the viability of the proposed project in the form of official letters of confirmation for internships, research at proposed institutions, acceptance to conferences, etc; A 1 - page (single-spaced) personal essay, explaining how the applicant would benefit from the Fellowship and the experience being proposed; Two letters of recommendation from relevant faculty members at the applicant's college or university. Application materials for the Leonard M. Rieser Research Fellowship must be received no later than March 1, 2002. Letters of notification to all applicants will be mailed on or around April 1, 2002. Completed applications or requests for an application form (if you are unable to download the form from the World Wide Web) should be mailed to: The Leonard M. Rieser Research Fellowship, Attn: Stephen Schwartz, Educational Foundation for Nuclear Science, 6042 South Kimbark Avenue, Chicago, IL 60637-2806. Please visit the Bulletin's web site at: http://www.thebulletin.org/fellowship.htm for additional details on and application materials for the fellowship. Winners will be announced in the July/August issue of the Bulletin of the Atomic Scientists and on our web site.

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New joint doctoral programs between the NIH-Oxford University and NIH-Cambridge University

We are pleased to announce the initiation of two new graduate programs in which we encourage your participation:

1. Oxford University-National Institutes of Health Scholars in Biomedical Research. This program was launched late last year with applications from students already in training at NIH and 2 Scholars are presently enrolled. This year we will have a national search for outstanding candidates and up to 4 new Scholars will be appointed.

2. Cambridge University-National Institutes of Health Health Science Scholars. This is a new program that will be inaugurated this year and will enroll 2 Scholars selected from a national applicant pool. A more complete description of the programs and a list of FAQs from last year's recruitment is attached. You can apply on the GPP web site at: http://gpp.nih.gov and send an email to Patty McCarthy about the specific program you are interested in at: McCarthy@OD.NIH.GOV. You can apply to both programs. If you have any questions, you can contact Michael Lenardo at: lenardo@nih.gov.

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EMPLOYMENT OPPORTUNITIES

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Research Scientist Gambro BCT. Responsible for the oversight of facilities and staff associated with photochemical research in PET program. The scope of work will include elucidation of mechanisms of action involved with photochemical procedures for the inactivation of pathogens in blood. Will conduct research in protein chemistry and nucleic acid chemistry designed to elucidate reaction pathways and consequences of photochemical or chemical treatment of blood products. This individual will be responsible for the organization and execution of scientific studies involving basic mechanisms of the chemistry and physics associated with the PET process. On site and external contract laboratory work associated with research and development studies will also be included in primary activities. This individual will be responsible for the organization of facilities in compliance with regulatory and OSHA requirements including facility construction, equipment needs and staff training relating to the use of photochemical and chemical research. Reports to the Chief Scientist of the PET program. Minimum knowledge required/qualifications: A graduate degree in a scientific or medical field is required; Minimally 6 - 10 years industry and corporate experience desirable, (beyond formal education or equivalent). This should include experience with advanced research involving viruses and bacteria; Extensive knowledge of scientific requirements associated with chemistry and photochemistry facilities including organization, equipment and certification processes; Extensive knowledge of leading edge developments and state-of-the-art technology as represented by an extensive publication in the field of chemistry and photochemistry; Excellent written and oral communications, and proven ability to establish working relationships with all levels of clinical/technical people; Sound scientific approach to evaluations and problem solving; Ability to work independently and travel as necessary; Experience in a leadership role and management of technical staff involved with high level academic or industrial research. Responsible for the oversight of chemical and photochemical research facilities including compliance with all regulatory and certification requirements; Responsible for training of staff necessary to maintain an effective research program in the area of photochemical studies; Responsible for the preparation of written and oral reports for internal and external presentation at scientific and technical meetings; Responsible for preparation of sections of regulatory filing documents related to studies elucidating the mechanism of action of photosensitizers and photochemical processes; Responsible for technical representation of research results before regulatory and customer groups as required by regulatory and marketing functions; Responsible for evaluation of new methodologies associated with inactivation techniques for virus and bacteria and establishment of these methods for use in development projects; Responsible for the preparation of technical reports relating to chemistry and photochemical studies; Responsible for the preparation of research protocols and execution of research involving virus and bacteria inactivation and replication and understanding of photochemical mechanisms including interactions and effects with proteins and nucleic acids; Maintains state-of-the-art knowledge by attending relevant meetings and visiting key clinicians and investigators; Analyzes and reports on these experiences to development group; Works with management team, as requested, to evaluate scientific related aspects of new ventures involving chemical or photochemical processes; Performs independent evaluation, selection, and application in making adaptations and modifications to project work; Has total project leadership responsibilities relating to photochemistry projects in support of PET program according to defined program objectives; Develops, mentors, and provides work direction to technicians, engineers, specialists, or scientists; Interfaces with industry representatives, customers, and regulatory agencies on project matters; Works with cross-functional teams to accomplish set goals in established time periods. Required knowledge/qualifications: The preferred education is a Ph.D. degree in chemistry , photochemistry or photophysics. An M.D. degree with experience in these fields is also preferred; At least 5 years experience in a biomedical, academic, or industrial environment is required; Extensive knowledge of chemistry and photochemistry is required. Knowledge of blood products and protein biology is highly desired. For additional information please contact: Raymond P. Goodrich, Ph.D., Chief Science Officer, Gambro BCT, 10811 W. Collins Avenue, Lakewood, CO 80227, (303) 205-2680 phone, (303) 239-2389 fax.

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Kalamazoo College seeks an instructor in Biochemistry to teach one course and associated laboratory for the spring 2002 term (April 1, 2002 - June 12, 2002). Graduate degree in biochemistry or closely related field required. Qualified applicants must have taken a broad range of biochemistry courses. Candidates are expected to have high aptitude for and interest in undergraduate teaching. To ease preparation and to maintain consistency with other sections of this course offered throughout the year, the visiting professor will teach from the same textbook and use a similar syllabus and laboratory manual as the other courses. Kalamazoo College is a highly selective, nationally known, undergraduate liberal arts college. Completed applications will be reviewed until the position is filled. Send curriculum vitae, undergraduate and graduate transcripts (unofficial acceptable), a detailed statement of teaching philosophy and goals, and two letters of recommendation to: Greg Slough, Chair, Department of Chemistry, Kalamazoo College, 1200 Academy Street, Kalamazoo, MI 49006-3295. For more information about the College, see our web site at http://www.kzoo.edu.

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NMR specialist / Group Leader. For the daily management of Structure Analysis. Organon, part of Akzo Nobel's pharma group, develops, produces and sells pharmaceuticals worldwide. It employs 12,000. The company searches intensively for innovative products: an R&D operation with 2,200 professionals in the Netherlands, Scotland, France, Japan and the U.S. The Dept. of Analytical Chemistry for Development (ACD) in the Netherlands, monitors the quality of drug substance, active compounds, and new chemical/biological entities (NCE/NBE). The ACD's Structure Analysis Section analyzes the chemical structure of NCE/NBEs, impurities and metabolites using techniques like NMR, IR, Raman and MS/MS. The Structure Analysis Section has 3 project groups using spectroscopy to solve compound-specific problems. As a group leader, you will see to the daily management of your team, and also to NMR instrumentation in the ACD (400 and 600 MHz spectrometer, including solid/liquid state NMR and LC-NMR), monitoring relevant developments and initiating/conducting/managing methodological research in the field of NMR spectroscopy. Ph.D. in chemistry specializing in (solid state or liquid) NMR spectroscopy. A good understanding of NMR instrument/software technology, the design/application of dedicated pulse experiments and experience in structure and conformation analyses are essential. Relevant experience with IR, Raman or MS is desirable. You are enthusiastic, inquisitive, focused on solving analytical problems, a good team player, and able to supervise and motivate people. For details, call: Dr. F. Croizet or Dr. M. Honing at the Structure Analysis Section, on +31 412-661130 and +31 412-663604 or e-mail: francois.croizet@organon.com or maarten.honing@organon.com. Please send your letter with CV within 14 days, stating vacancy number GGO 01-36, to G. Goorsenberg, HR Dept., NV Organon, P.O. Box 20, 5340 BH Oss, Holland. E-mail: gerard.goorsenberg@organon.com.

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Merck Research Laboratories (Rahway, NJ). The candidate will complete bioanalytical method development, validation, and quantitative LC/MS/MS analysis of pharmaceutical products in biological matrices (e.g., plasma, serum, urine, whole blood). The LC/MS/MS quantitative assays will be performed in support of preclinical pharmacokinetics, toxicokinetics, and drug metabolism studies. Candidate should have a BS or MS in Chemistry, Biochemistry or a related Pharmaceutical Science. Excellent communication skills and a strong background in sample preparation, HPLC operation, and troubleshooting are required. Experience in automation/robotics, mass spectrometry, and GLP regulation is preferred (but not required). Training opportunities for the operation of ion-trap and triple quadrupole mass spectrometers will be provided. Please forward a recent CV along with names and telephone numbers of 3 references to: Ray Bakhtiar at: ray_bakhtiar@merck.com.

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FACULTY POSITIONS/TEMPORARY FACULTY/ACADEMIC POSITIONS

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The Department of Medicinal Chemistry at the University of Michigan solicits applications for the John Gideon Searle Professor of Medicinal Chemistry. This prestigious, endowed Chair has a history of supporting internationally known scholars in the pharmaceutical sciences. The Interdepartmental Program in Medicinal Chemistry at Michigan has long been recognized as one of the leading programs in the country. The successful candidate will be expected to provide leadership to build on this tradition. This program involves faculty and students from not only the Department of Medicinal Chemistry in the College of Pharmacy but also departments in the College of Literature, Science, and the Arts, and the Medical School. Potential areas of research may include, but are not limited to, synthetic organic chemistry, mechanistic enzymology, and structural biochemistry, all of which should be focused on exciting medicinal targets and rationales. The successful candidate will be expected to maintain a vigorous, externally funded research program and to participate in teaching programs both at the graduate and undergraduate level. Applications, including a curriculum vitae and a list of at least five references should be sent to: Prof. James IC Coward, Chair, Department of Medicinal Chemistry, University of Michigan, 428 Church St., Ann Arbor, MI 48109-1065. Applications will be reviewed commencing December 1, 2001 and will continue until the position is filled. Web site: http://www.umich.edu/~phamacy/MedChem/.

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POSTDOCTORAL POSITION AND/OR JOBS

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Postdoctoral positions. The chemical sensors group, University of Cincinnati. The Chemical Sensors Group invites applications for immediately available postdoctoral positions. Of particular interest are the areas of optical sensors, electrochemical sensors, bio-nanotechnology or nano-structured materials for sensing and spectroelectrochernical sensing, although superior candidates in other areas related to sensors should also apply. Candidates will have a PhD in chemistry or a discipline relevant to chemical sensors. Applicants should submit a letter of application, a curriculum vita, and three letters of recommendation to: Prof. Carl J. Seliskar, Chemistry Department, PO Box 210172, University of Cincinnati, Cincinnati, OH 45221-0172. Applications will be reviewed as received.

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Please submit all newsletter information or address changes to: goldade@chem.wisc.edu or 262-0293. Thank You.

DETAILS ARE AVAILABLE IN ROOM 1146.

NEXT NEWSLETTER IS ON JANUARY 22nd, 2002.